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Aqueous Misdirection After Trabeculectomy in a Down Syndrome Patient With Angle-closure Glaucoma
Journal article   Open access   Peer reviewed

Aqueous Misdirection After Trabeculectomy in a Down Syndrome Patient With Angle-closure Glaucoma

Austin R Fox, Wallace L M Alward and John H Fingert
Journal of glaucoma, Vol.30(5), pp.e269-E270
05/01/2021
DOI: 10.1097/IJG.0000000000001831
PMID: 33710067
url
https://doi.org/10.1097/IJG.0000000000001831View
Published (Version of record) Open Access

Abstract

Down syndrome is a genetic disease caused by trisomy of chromosome 21 that is characterized by numerous systemic abnormalities including intellectual disability, stereotypical facies, and congenital heart malformations. Ocular abnormalities are commonly seen with Down syndrome including corneal disease (keratoconus), refractive error, and atypical irides (Brushfield spots). We report the first case of aqueous misdirection in a patient with Down syndrome after trabeculectomy. Patients with Down syndrome often have small, hyperopic eyes with narrow iridocorneal angles and may be at increased risk for aqueous misdirection associated with surgical procedures. Awareness of this risk may aid surgical planning and postoperative management.

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