Journal article
Arginine Vasopressin and Acute, Intravascular Volume Expansion in the Human Fetus
Fetal diagnosis and therapy, Vol.4(2-3), pp.69-72
1989
DOI: 10.1159/000263425
Abstract
There is presently no information concerning the ontogeny and control of arginine vasopressin (AVP) in the human fetus. AVP was measured in 22 nonanemic control fetuses and 7 fetuses with hemolytic anemia undergoing 13 intravascular transfusions. Each transfused fetus received pancuronium (0.3 mg/kg) and furosemide (2 mg/kg). Compared to the control group of nonanemic fetuses with hemolytic disease, AVP was significantly lower in the anemic fetus prior to transfusion (2.6 ± 0.4 μU/ml versus 10.4 ± 4.1 μU/ml, p < 0.05). This suggests that hemolytic anemia is associated with a relative increase in fetal intravascular volume. Intravascular transfusion was associated with a significant increase in AVP (p < 0.05). These findings could not be explained by changes in either blood pressure, plasma osmolality, or fetal oxygenation.
Details
- Title: Subtitle
- Arginine Vasopressin and Acute, Intravascular Volume Expansion in the Human Fetus
- Creators
- Carl P. Weiner - Society for Maternal-Fetal MedicineFrancine Smith - University of IowaJean E. Robillard - Society for Maternal-Fetal Medicine
- Resource Type
- Journal article
- Publication Details
- Fetal diagnosis and therapy, Vol.4(2-3), pp.69-72
- DOI
- 10.1159/000263425
- ISSN
- 1015-3837
- eISSN
- 1421-9964
- Number of pages
- 4
- Language
- English
- Date published
- 1989
- Academic Unit
- Molecular Physiology and Biophysics; Nephrology, Dialysis and Transplantation; Stead Family Department of Pediatrics; Medicine Administration
- Record Identifier
- 9984773399802771
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