Journal article
Arrhythmias in the Heart Transplant Patient
Arrhythmia & electrophysiology review, Vol.3(3), pp.149-155
11/01/2014
DOI: 10.15420/aer.2014.3.3.149
PMCID: PMC4711495
PMID: 26835083
Abstract
Orthotopic heart transplantation (OHT) is currently the most effective long-term therapy for patients with end-stage cardiac disease, even as left ventricular devices show markedly improved outcomes. As surgical techniques and immunosuppressive regimens have been refined, short-term mortality caused by sepsis has decreased, while morbidity caused by repeated rejection episodes and vasculopathy has increased, and is often manifested by arrhythmias. These chronic transplant complications require early and aggressive multidisciplinary treatment. Understanding the relationship between arrhythmias and these complications in the acute and chronic stages following OHT is critical in improving patient prognosis, as arrhythmias may be the earliest or sole presentation. Finally, decentralised/ denervated hearts represent a unique opportunity to investigate the underlying mechanisms of arrhythmias.
Details
- Title: Subtitle
- Arrhythmias in the Heart Transplant Patient
- Creators
- David Hamon - UCLA HealthJane Taleski - Ss. Cyril and Methodius University in SkopjeMarmar Vaseghi - UCLA HealthKalyanam Shivkumar - UCLA HealthNoel G Boyle - UCLA Health
- Resource Type
- Journal article
- Publication Details
- Arrhythmia & electrophysiology review, Vol.3(3), pp.149-155
- DOI
- 10.15420/aer.2014.3.3.149
- PMID
- 26835083
- PMCID
- PMC4711495
- NLM abbreviation
- Arrhythm Electrophysiol Rev
- ISSN
- 2050-3369
- eISSN
- 2050-3377
- Publisher
- Radcliffe Cardiology
- Language
- English
- Date published
- 11/01/2014
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984695667002771
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