Journal article
Arterial pressure is not reflective of right ventricular function in neonates with hypoxic ischemic encephalopathy treated with therapeutic hypothermia
Journal of perinatology, Vol.43(2), pp.162-167
02/2023
DOI: 10.1038/s41372-022-01567-3
PMID: 36460796
Abstract
Aim: to evaluate the correlation of recovery of arterial pressure with physiological recovery among patients with hypoxic ischemic encephalopathy undergoing therapeutic hypothermia.
Methods: At 24 h postnatal age, we compared 53 neonates of whom 22 (41%) were inotrope-treated to those untreated with cardiovascular medications.
Results: Inotrope-treated patients had persistent severe right ventricular (RV) dysfunction and evidence of abnormal brain tissue oxygen delivery, despite recovered arterial pressure.
Conclusion: Arterial pressure is not reflective of RV function and the need for inotropic agents may be reflective of abnormal brain tissue oxygen delivery.
Details
- Title: Subtitle
- Arterial pressure is not reflective of right ventricular function in neonates with hypoxic ischemic encephalopathy treated with therapeutic hypothermia
- Creators
- R. E. Giesinger - University of IowaA. F. El-Khuffash - Royal College of Surgeons in IrelandP. J. McNamara - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of perinatology, Vol.43(2), pp.162-167
- DOI
- 10.1038/s41372-022-01567-3
- PMID
- 36460796
- ISSN
- 0743-8346
- eISSN
- 1476-5543
- Language
- English
- Electronic publication date
- 12/02/2022
- Date published
- 02/2023
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology; Internal Medicine
- Record Identifier
- 9984354157102771
Metrics
33 Record Views