Journal article
Arteriovenous malformation within an isocitrate dehydrogenase 1 mutated anaplastic oligodendroglioma
Surgical neurology international, Vol.6(Suppl 9), pp.S295-S299
09/01/2015
DOI: 10.4103/2152-7806.159373
PMCID: PMC4496836
PMID: 26167373
Abstract
Background: The co-occurrence of intracranial arteriovenous malformations (AVMs) and cerebral neoplasms is exceedingly rare but may harbor implications pertaining to the molecular medicine of brain cancer pathogenesis.
Case Description: Here, we present a case of de novo AVM within an isocitrate dehydrogenase 1 mutated anaplastic oligodendroglioma (WHO Grade III) and review the potential contribution of this mutation to aberrant angiogenesis as an interesting case study in molecular medicine.
Conclusion: The co-occurrence of an IDH1 mutated neoplasm and AVM supports the hypothesis that IDH1 mutations may contribute to aberrant angiogenesis and vascular malformation.
Details
- Title: Subtitle
- Arteriovenous malformation within an isocitrate dehydrogenase 1 mutated anaplastic oligodendroglioma
- Creators
- Grace Lai - School of Medicine, University of California, San Diego, CA, USAKarra A Muller - Department of Pathology, University of California, San Diego, CA, USABob S Carter - Department of Neurosurgery, University of California, San Diego, CA, USAClark C Chen - Department of Neurosurgery, University of California, San Diego, CA, USA
- Resource Type
- Journal article
- Publication Details
- Surgical neurology international, Vol.6(Suppl 9), pp.S295-S299
- DOI
- 10.4103/2152-7806.159373
- PMID
- 26167373
- PMCID
- PMC4496836
- NLM abbreviation
- Surg Neurol Int
- ISSN
- 2152-7806
- eISSN
- 2152-7806
- Publisher
- Medknow Publications & Media Pvt Ltd; India
- Language
- English
- Date published
- 09/01/2015
- Academic Unit
- Pathology
- Record Identifier
- 9984047756202771
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