Journal article
Arthroplasty studies with greater than 1000 participants: analysis of follow-up methods
Arthroplasty today, Vol.5(2), pp.243-250
06/2019
DOI: 10.1016/j.artd.2019.03.006
PMCID: PMC6588815
PMID: 31286051
Abstract
The use of patient-reported outcome measures (PROMs) has become a mainstay of orthopedic joint arthroplasty research. Large studies with >1000 participants are vital to orthopedic research, as they allow for comprehensive multivariable analysis. Achieving high follow-up rates minimizes potential response bias. Maintaining adequate follow-up rates becomes more challenging as sample size increases. We aimed to systematically review the present literature to determine the follow-up rates of large cohorts/registries of total joint arthroplasty patients and to identify factors associated with successful collection of PROMs.
A comprehensive literature search of PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Inclusion criteria were: ≥1000 participants, ≥6 months of postoperative follow-up, and use of validated PROMs postoperatively.
Of 720 abstracts screened, 21 studies met inclusion criteria. Only 2 studies reported achieving a PROM follow-up rate ≥80%, but neither collected PROMs preoperatively. The median rate of follow-up was 70%, and the median number of patients was 2970. Only 38% (8 of 21) of studies collected baseline PROMs prior to surgery.
Very few studies in the present literature have collected validated PROMs on ≥1000 patients with ≥80% follow-up; these parameters are conducive to comprehensive multivariable analysis, while maintaining study validity and avoiding follow-up bias. Federal funding and a central coordinating site may be helpful in achieving follow-up in studies of this magnitude.
Level III, systematic review of studies with Level of Evidence I-III.
Details
- Title: Subtitle
- Arthroplasty studies with greater than 1000 participants: analysis of follow-up methods
- Creators
- Muhammad B. Tariq - Cleveland ClinicJosé F. Vega - Cleveland Clinic Lerner College of MedicineRobert Westermann - Cleveland ClinicMorgan Jones - Cleveland ClinicKurt P. Spindler - Cleveland Clinic
- Resource Type
- Journal article
- Publication Details
- Arthroplasty today, Vol.5(2), pp.243-250
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.artd.2019.03.006
- PMID
- 31286051
- PMCID
- PMC6588815
- ISSN
- 2352-3441
- eISSN
- 2352-3441
- Language
- English
- Date published
- 06/2019
- Academic Unit
- Orthopedics and Rehabilitation; Athletic Training Program
- Record Identifier
- 9984304681802771
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