Journal article
Artificial intelligence for automatic detection of basal cell carcinoma from frozen tissue tangential biopsies
Clinical and experimental dermatology, Vol.49(7), pp.719-721
06/15/2023
DOI: 10.1093/ced/llad209
Abstract
Evaluation of basal cell carcinoma (BCC) involves tangential biopsies of a suspicious lesion that is sent for frozen sections and evaluated by a Mohs micrographic surgeon. Advances in artificial intelligence (AI) have made possible the development of sophisticated clinical decision support systems to provide real-time feedback to clinicians which could have a role in optimizing the diagnostic workup of BCC. There were 287 annotated whole-slide images of frozen sections from tangential biopsies, of which 121 contained BCC, that were used to train and test an AI pipeline to recognize BCC. Regions of interest were annotated by a senior dermatology resident, experienced dermatopathologist, and experienced Mohs surgeon, with concordance of annotations noted on final review. Final performance metrics included a sensitivity and specificity of 0.73 and 0.88, respectively. Our results on a relatively small dataset suggest the feasibility of developing an AI system to aid in the workup and management of BCC.
Details
- Title: Subtitle
- Artificial intelligence for automatic detection of basal cell carcinoma from frozen tissue tangential biopsies
- Creators
- Dennis H Murphree - Mayo Clinic in ArizonaYong-Hun Kim - Mayo Clinic in ArizonaKirk A Sidey - University of IowaNneka I Comfere - Mayo ClinicNahid Y Vidal - Mayo Clinic in Arizona
- Resource Type
- Journal article
- Publication Details
- Clinical and experimental dermatology, Vol.49(7), pp.719-721
- DOI
- 10.1093/ced/llad209
- eISSN
- 1365-2230
- Language
- English
- Electronic publication date
- 06/15/2023
- Academic Unit
- Dermatology
- Record Identifier
- 9984436456102771
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