Journal article
Assessing the 210At impurity in the production of 211At for radiotherapy by 210Po analysis via isotope dilution alpha spectrometry
Applied radiation and isotopes, Vol.64(10), pp.1365-1369
2006
DOI: 10.1016/j.apradiso.2006.02.046
PMID: 16563782
Abstract
A method for assessing the impurity
210At in cyclotron-produced
211At via isotope dilution alpha spectrometry is presented. The activity of
210At is quantified by measuring the activity of daughter nuclide
210Po. Counting sources are prepared by spontaneous deposition of Po on a silver disc. Activity of
210At (at the time of
210Po maximum activity) is found to be 83.5±9.0
Bq, corresponding to an atom ratio (
210At:
211At at the time of distillation) of 0.010±0.007% (
k
=
2
). The method produces high-quality alpha spectra, with baseline alpha-peak resolution and chemical yields of greater than 85%.
Details
- Title: Subtitle
- Assessing the 210At impurity in the production of 211At for radiotherapy by 210Po analysis via isotope dilution alpha spectrometry
- Creators
- Michael K Schultz - National Institute of Standards and Technology, Radioactivity Group, 100 Bureau Drive MS8462, Gaithersburg, MD 21702, USAMichelle Hammond - National Institute of Standards and Technology, Radioactivity Group, 100 Bureau Drive MS8462, Gaithersburg, MD 21702, USAJeffrey T Cessna - National Institute of Standards and Technology, Radioactivity Group, 100 Bureau Drive MS8462, Gaithersburg, MD 21702, USAPaul Plascjak - National Institutes of Health, Cyclotron Facilities, 10 Center Drive, Bethesda, MD, USABruce Norman - National Institute of Standards and Technology, Radioactivity Group, 100 Bureau Drive MS8462, Gaithersburg, MD 21702, USALawrence Szajek - National Institutes of Health, Cyclotron Facilities, 10 Center Drive, Bethesda, MD, USAKayhan Garmestani - National Institutes of Health, Cyclotron Facilities, 10 Center Drive, Bethesda, MD, USABrian E Zimmerman - International Atomic Energy Agency, Dosimetry and Radiation Physics Section, Wagramer Strasse 5, P.O. Box 100, A-1400 Vienna, AustriaMichael Unterweger - National Institute of Standards and Technology, Radioactivity Group, 100 Bureau Drive MS8462, Gaithersburg, MD 21702, USA
- Resource Type
- Journal article
- Publication Details
- Applied radiation and isotopes, Vol.64(10), pp.1365-1369
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.apradiso.2006.02.046
- PMID
- 16563782
- ISSN
- 0969-8043
- eISSN
- 1872-9800
- Language
- English
- Date published
- 2006
- Academic Unit
- Radiology; Stead Family Department of Pediatrics; Radiation Oncology
- Record Identifier
- 9984046909702771
Metrics
23 Record Views