Journal article
Association Between Hematological Indices and Coronary Calcification in Symptomatic Patients without History of Coronary Artery Disease
North American journal of medical sciences, Vol.6(9), pp.433-439
09/01/2014
DOI: 10.4103/1947-2714.141625
PMCID: PMC4193148
PMID: 25317386
Abstract
Background: Atherosclerotic coronary artery disease (CAD) has long been shown to involve chronic low-grade subclinical inflammation. However, whether there is association between hematological indices assessed by complete blood count (CBC) and coronary atherosclerotic burden has not been well studied. Materials and Methods: Consecutive 868 patients without known CAD who presented with acute chest pain to emergency department and underwent coronary artery calcium (CAC) scoring evaluation by multi-detector cardiac computed tomography were included in our study. Clinical characteristics and CBC indices were compared among different CAC groups. Results: The cohort comprised 60% male with a mean age of 61 (SD = 14) years. Median Framingham risk of CAD was 4% (range 1-16%). Median CAC score was 0 (IQR 0-43). Higher CAC groups had significantly higher Framingham risk of CAD than lower CAC groups (P < 0.001). Among different CAC categories, there was no statistically significant difference in hemoglobin level (p 0.45), mean corpuscular volume (p 0.43), mean corpuscular hemoglobin (p 0.28), mean corpuscular hemoglobin volume (p 0.36), red cell distribution width (0.42), total white blood cell counts (p 0.291), neutrophil counts (p 0.352), lymphocyte counts (p 0.92), neutrophil to lymphocyte ratio (p 0.68), monocyte count (p 0.48), and platelet counts (p 0.25). Conclusion: Our study did not detect significant association between hematological indices assessed with CBC and coronary calcification in symptomatic patients without known CAD.
Details
- Title: Subtitle
- Association Between Hematological Indices and Coronary Calcification in Symptomatic Patients without History of Coronary Artery Disease
- Creators
- Kongkiat Chaikriangkrai - Methodist HospitalMahwash Kassi - Methodist HospitalSama Alchalabi - Houston MethodistSayf Khaleel Bala - Houston MethodistRosalyn Adigun - Methodist HospitalSharleen Botero - Houston MethodistSu Min Chang - Houston Methodist
- Resource Type
- Journal article
- Publication Details
- North American journal of medical sciences, Vol.6(9), pp.433-439
- Publisher
- MEDKNOW PUBLICATIONS & MEDIA PVT LTD
- DOI
- 10.4103/1947-2714.141625
- PMID
- 25317386
- PMCID
- PMC4193148
- ISSN
- 2250-1541
- eISSN
- 1947-2714
- Number of pages
- 7
- Language
- English
- Date published
- 09/01/2014
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984359820602771
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