Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina

Oluwole Adeyemi Babatunde; Whitney E Zahnd; Jan M Eberth; Andrew B Lawson; Swann Arp Adams; Eric Adjei Boakye; Melanie S Jefferson; Caitlin G Allen; John L Pearce; Hong Li; Chanita Hughes Halbert

doi:10.3390/ijerph182211824

Back

Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina

Journal article

Open access

Peer reviewed

Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina

Oluwole Adeyemi Babatunde, Whitney E Zahnd, Jan M Eberth, Andrew B Lawson, Swann Arp Adams, Eric Adjei Boakye, Melanie S Jefferson, Caitlin G Allen, John L Pearce, Hong Li, …

International journal of environmental research and public health, Vol.18(22), p.11824

11/11/2021

DOI: 10.3390/ijerph182211824

PMCID: PMC8625868

PMID: 34831579

Files and links (1)

url

https://doi.org/10.3390/ijerph182211824View

Published (Version of record) Open Access

Abstract

The purpose of this study was to examine the association between neighborhood social deprivation and individual-level characteristics on breast cancer staging in African American and white breast cancer patients. We established a retrospective cohort of patients with breast cancer diagnosed from 1996 to 2015 using the South Carolina Central Cancer Registry. We abstracted sociodemographic and clinical variables from the registry and linked these data to a county-level composite that captured neighborhood social conditions—the social deprivation index (SDI). Data were analyzed using chi-square tests, Student’s t-test, and multivariable ordinal regression analysis to evaluate associations. The study sample included 52,803 female patients with breast cancer. Results from the multivariable ordinal regression model demonstrate that higher SDI (OR = 1.06, 95% CI: 1.02–1.10), African American race (OR = 1.35, 95% CI: 1.29–1.41), and being unmarried (OR = 1.17, 95% CI: 1.13–1.22) were associated with a distant stage at diagnosis. Higher tumor grade, younger age, and more recent year of diagnosis were also associated with distant-stage diagnosis. As a proxy for neighborhood context, the SDI can be used by cancer registries and related population-based studies to identify geographic areas that could be prioritized for cancer prevention and control efforts.

Details

Title: Subtitle: Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina
Creators: Oluwole Adeyemi Babatunde
Whitney E Zahnd
Jan M Eberth
Andrew B Lawson
Swann Arp Adams
Eric Adjei Boakye
Melanie S Jefferson
Caitlin G Allen
John L Pearce
Hong Li
Chanita Hughes Halbert
Resource Type: Journal article
Publication Details: International journal of environmental research and public health, Vol.18(22), p.11824
DOI: 10.3390/ijerph182211824
PMID: 34831579
PMCID: PMC8625868
NLM abbreviation: Int J Environ Res Public Health
ISSN: 1660-4601
eISSN: 1660-4601
Grant note: DOI: 10.13039/100000002, name: National Institutes of Health, award: 5 K00 CA222722 04
Language: English
Date published: 11/11/2021
Academic Unit: Health Management and Policy
Record Identifier: 9984221747502771

Metrics

18 Record Views

24 Times Cited - Web of Science