Journal article
Association between Semen Exposure and Incident Bacterial Vaginosis
Infectious diseases in obstetrics and gynecology, Vol.2011, pp.842652-10
2011
DOI: 10.1155/2011/842652
PMCID: PMC3235572
PMID: 22190844
Abstract
Objective
. To identify correlates of incident bacterial vaginosis (BV) diagnosed with Nugent scoring among high-risk women.
Study Design
. We conducted both cohort and case-crossover analyses, stratified by HIV infection status, based on 871 HIV-infected and 439 HIV-uninfected participants in the HIV Epidemiology Research Study, conducted in 4 US sites in 1993–2000.
Results
. BV incidence was 21% and 19% among HIV-infected and -uninfected women, respectively. Fewer correlates of BV were found with case-crossover than with cohort design. Reporting frequent coitus (regardless of consistency of condom use) was correlated with BV in cohort analyses but not in case-crossover analyses. The sole correlate of BV in both types of analyses was the detection of spermatozoa on Gram stain, which is a marker of semen exposure.
Conclusion
. The inconsistent association between condom use and BV in prior studies could be from reporting bias. We found evidence of a relationship between semen exposure and incident BV.
Details
- Title: Subtitle
- Association between Semen Exposure and Incident Bacterial Vaginosis
- Creators
- Maria F. Gallo - Centers for Disease Control and PreventionLee Warner - Johns Hopkins University School of MedicineCaroline C. King - Johns Hopkins University School of MedicineJack D. Sobel - Wayne State UniversityRobert S. Klein - Icahn School of Medicine at Mount SinaiSusan Cu-Uvin - Miriam HospitalAnne M. Rompalo - Johns Hopkins Bayview Medical CenterDenise J. Jamieson - Johns Hopkins University School of Medicine
- Resource Type
- Journal article
- Publication Details
- Infectious diseases in obstetrics and gynecology, Vol.2011, pp.842652-10
- DOI
- 10.1155/2011/842652
- PMID
- 22190844
- PMCID
- PMC3235572
- NLM abbreviation
- Infect Dis Obstet Gynecol
- ISSN
- 1064-7449
- eISSN
- 1098-0997
- Publisher
- Hindawi Publishing Corporation
- Grant note
- DOI: 10.13039/100000030, name: Centers for Disease Control and Prevention, award: U64/CCU106795, U64/CCU206798, U64/CCU306802, U64/CCU506831
- Language
- English
- Date published
- 2011
- Academic Unit
- Obstetrics and Gynecology; VPMA - Administration
- Record Identifier
- 9984446061302771
Metrics
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