Journal article
Association of Exposure to Ambient Fine Particulate Matter Constituents With Semen Quality Among Men Attending a Fertility Center in China
Environmental science & technology, Vol.53(10), pp.5957-5965
05/21/2019
DOI: 10.1021/acs.est.8b06942
PMID: 31013428
Abstract
Ambient fine particulate matter (PM2.5) exposure has been linked to decreased semen quality, but the associations between PM2.5 constituent exposures and semen quality remain unknown. We enrolled 1081 men whose partners underwent assisted reproductive technology procedures in Wuhan, China in 2014–2015, and examined their semen quality. Daily average concentrations of PM2.5 constituents including 10 metals/metalloid elements and 4 water-soluble ions were continuously determined for 1 week per month at 2 fixed monitoring stations. Linear mixed models were used to examine the associations of exposures to PM2.5 and its constituents with semen quality. Each interquartile range (36.5 μg/m3) increase in PM2.5 exposure was significantly associated with 8.5% (95% CI: 2.3%, 14.4%) and 8.1% (95% CI: 0.7%, 15.0%) decrease in sperm concentration and total sperm number, respectively. Antimony, cadmium, lead, manganese, and nickel exposures were significantly associated with decreased sperm concentration, whereas manganese exposure was also significantly associated with decreased total motility. Nonsmokers were more susceptible to PM2.5 constituent exposures, especially for antimony and cadmium (all P for effect modification <0.05). These findings suggest that PM2.5 and certain constituents may adversely affect semen quality, especially sperm concentration, and provide new evidence to formulate pollution abatement strategies for male reproductive health.
Details
- Title: Subtitle
- Association of Exposure to Ambient Fine Particulate Matter Constituents With Semen Quality Among Men Attending a Fertility Center in China
- Creators
- Wei Bao - Department of Epidemiology, College of Public HealthXiji Huang - Hubei Provincial Center for Disease Control and PreventionBing Zhang - School of Public Health (Shenzhen)Li Wu - Huazhong University of Science and TechnologyYun Zhou - Huazhong University of Science and TechnologyYonggang Li - Hubei Provincial Hospital of Integrative MedicineXiang Mao - Wuhan Municipal Center for Disease Control and PreventionYing Chen - Hubei Provincial Center for Disease Control and PreventionJing Wang - Hubei UniversityPing Luo - Hubei Provincial Center for Disease Control and PreventionJixuan Ma - Huazhong University of Science and TechnologyHai Zhang - Hubei Provincial Center for Disease Control and PreventionZhe Peng - Hubei Provincial Center for Disease Control and PreventionXiuqing Cui - Hubei Provincial Center for Disease Control and PreventionShuguang Xie - Hubei Provincial Center for Disease Control and PreventionXixiang Huo - Hubei Provincial Center for Disease Control and PreventionMing Zhang - Tianjin Centers for Disease Control and PreventionTingming Shi - Hubei Provincial Center for Disease Control and PreventionYuewei Liu - Sun Yat-sen University
- Resource Type
- Journal article
- Publication Details
- Environmental science & technology, Vol.53(10), pp.5957-5965
- Publisher
- American Chemical Society
- DOI
- 10.1021/acs.est.8b06942
- PMID
- 31013428
- ISSN
- 0013-936X
- eISSN
- 1520-5851
- Grant note
- DOI: 10.13039/501100006606, name: Natural Science Foundation of Tianjin City, award: 15JCQNJC45100; name: Hubei Provincial Committee of the Communist Youth League of China; DOI: 10.13039/501100010846, name: Health and Family Planning Commission of Hubei Province, award: WJ2017M136, WJ2019Z016, WJ2015MA027
- Language
- English
- Date published
- 05/21/2019
- Academic Unit
- Epidemiology; Fraternal Order of Eagles Diabetes Research Center
- Record Identifier
- 9983995166202771
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