Journal article
Association of Mood and Anxiety Disorders and Opioid Prescription Patterns Among Postpartum Women
The American journal on addictions, Vol.29(6), pp.463-470
11/2020
DOI: 10.1111/ajad.13028
PMID: 32249527
Abstract
Postpartum women represent a large population with opioid exposure who also have an increased risk of experiencing mood and anxiety disorders. However, the effect that mood and anxiety disorders have on opioid use postpartum has received little attention in the literature. Therefore, the objective of this study was to examine the association of mood and anxiety disorders with filling opioid prescriptions within the first 3 months postpartum.
A retrospective cohort study (n = 25 279) was completed using claims data for a sample of privately insured women who gave birth in the state of Iowa. The interactive effects of mood and anxiety disorders and delivery mode on filling at least one and two or more opioid prescriptions were examined in logistic regression models.
The presence of mood and anxiety disorders among women who delivered vaginally increased their odds of filling at least one opioid fill by nearly 50% (odds ratio [OR]: 1.48, 95% confidence interval [CI]: 1.35-1.63) and by 20% (OR: 1.20, 95% CI: 1.00-1.43) among women with cesarean delivery.
Postpartum women with mood and anxiety disorders were more likely to fill opioid prescriptions postpartum compared to women without these conditions.
This study extends prior research by examining the intersection of risk of mood and anxiety disorders and opioid use postpartum. Findings from this study support the need for future research to identify the drivers of increased opioid use among postpartum women with mood and anxiety disorders. (Am J Addict 2020;29:463-470).
Details
- Title: Subtitle
- Association of Mood and Anxiety Disorders and Opioid Prescription Patterns Among Postpartum Women
- Creators
- Nichole Nidey - University of Cincinnati College of Medicine, Cincinnati, OhioRyan Carnahan - Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IowaKnute D Carter - Department of Biostatistics, University of Iowa College of Public Health, Iowa City, IowaLane Strathearn - Center for Disabilities and Development, University of Iowa Stead Family Children's Hospital, Iowa City, IowaWei Bao - Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IowaAndrea Greiner - Department of Obstetrics and Gynecology, University of Iowa Carver College of Medicine, Iowa City, IowaLaura Jelliffee-Pawlowski - Department of Epidemiology and Biostatistics, University of California San Francisco School of Medicine, San Francisco, CaliforniaKaren M Tabb - School of Social Work, University of Illinois at Urbana-Champaign, Urbana, IllinoisKelli Ryckman - Department of Epidemiology, University of Iowa College of Public Health, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- The American journal on addictions, Vol.29(6), pp.463-470
- DOI
- 10.1111/ajad.13028
- PMID
- 32249527
- NLM abbreviation
- Am J Addict
- ISSN
- 1055-0496
- eISSN
- 1521-0391
- Publisher
- England
- Language
- English
- Date published
- 11/2020
- Academic Unit
- Psychiatry; Stead Family Department of Pediatrics; Epidemiology; Iowa Neuroscience Institute; Biostatistics; Addiction Medicine; Craniofacial Anomalies Research Center; Nursing; Obstetrics and Gynecology; Developmental and Behavioral Pediatrics; Injury Prevention Research Center; Neuroscience and Pharmacology
- Record Identifier
- 9984070128402771
Metrics
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