Journal article
Association of Sleep Patterns and Lifestyles With Incident Hypertension: Evidence From a Large Population-Based Cohort Study
Frontiers in cardiovascular medicine, Vol.9, pp.847452-847452
04/01/2022
DOI: 10.3389/fcvm.2022.847452
PMCID: PMC9010545
PMID: 35433876
Abstract
BackgroundAdherence to a healthy lifestyle (no smoking, consuming a healthy diet, engaging in physical activity, and maintaining a healthy weight) is recommended in current guidelines for hypertension prevention. However, evidence regarding the association between sleep behaviors, independently and jointly with traditional lifestyle factors, and the risk of hypertension is limited. MethodsThis prospective study included 165,493 participants who are free of hypertension at baseline from the UK Biobank. Sleep behaviors, including chronotype, sleep duration, insomnia, snoring, and daytime sleepiness were used to construct a healthy sleep score. We also derived a healthy lifestyle score based on smoking status, diet quality, physical activity, and body mass index (BMI). Cox proportional hazards regression models and competing risk analyses were used to estimate the associations of the healthy sleep score and healthy lifestyle score with the risk of hypertension. The population attributable risk percent (PAR%) was estimated for increased cases of hypertension due to poor adherence to a healthy sleep pattern or a healthy lifestyle. ResultsA total of 10,941 incident hypertension cases were documented during a median of 11.8 years of follow-up. The multivariable-adjusted hazard ratio (HR) for hypertension was 0.58 [95% confidence interval (CI): 0.52, 0.65] for participants with a sleep score of 5 compared with 0-1, and 0.48 (95% CI: 0.43, 0.54) for participants with a lifestyle score of 4 compared with those who scored 0. For joint association, those with a poor sleep pattern and a poor lifestyle had the highest risk of hypertension [HR: 2.41 (95% CI: 2.12, 2.74)]. PAR% was 14.7% (95% CI: 12.3%, 17.1%), 20.1% (95% CI: 17.6%, 22.6%), and 31.7% (95% CI: 27.6%, 35.6%) for poor adherence to a healthy sleep pattern, a healthy lifestyle, and the combination of a healthy sleep pattern and a healthy lifestyle. ConclusionBoth a healthy sleep pattern and a healthy lifestyle were associated with a lower risk of hypertension, and the benefits of adhering to a healthy sleep pattern complement the well-established lifestyle for the optimal primary prevention of hypertension. These findings support the current perspective that a healthy sleep pattern is an important part of a healthful and productive lifestyle for hypertension prevention.
Details
- Title: Subtitle
- Association of Sleep Patterns and Lifestyles With Incident Hypertension: Evidence From a Large Population-Based Cohort Study
- Creators
- Yanling Lv - Huazhong University of Science and TechnologyGuanhua Jiang - Huazhong University of Science and TechnologyXiao Tan - Karolinska InstitutetWei Bao - University of IowaLiangkai Chen - Huazhong University of Science and Technology HospitalLiegang Liu - Huazhong University of Science and Technology
- Resource Type
- Journal article
- Publication Details
- Frontiers in cardiovascular medicine, Vol.9, pp.847452-847452
- DOI
- 10.3389/fcvm.2022.847452
- PMID
- 35433876
- PMCID
- PMC9010545
- NLM abbreviation
- Front Cardiovasc Med
- ISSN
- 2297-055X
- eISSN
- 2297-055X
- Publisher
- Frontiers Media Sa
- Number of pages
- 11
- Grant note
- 2020YFC2006300 / National Key Research and Development Program of China 81820108027 / National Natural Science of China; National Natural Science Foundation of China (NSFC)
- Language
- English
- Date published
- 04/01/2022
- Academic Unit
- Epidemiology
- Record Identifier
- 9984364539602771
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