Journal article
Association of exotoxin-producing Group A streptococci and severe disease in children
The Pediatric infectious disease journal, Vol.10(5), pp.351-354
05/1991
DOI: 10.1097/00006454-199105000-00001
PMID: 2067883
Abstract
Clinical features and microbiologic data on all cases of serious (hospitalized) Group A streptococcal infections in children managed at our institution between 1985 and 1988 are presented. All 6 cases were caused by toxin-producing strains. Four of 6 were toxin A-producing strains whereas none of 58 community-acquired (Group A streptococcal) pharyngeal isolates in the same period was a toxin A producer. A review of the literature on the incidence of toxin A-producing strains provides information suggesting a resurgence of such strains in the late 1980s after a relative disappearance in the preceding 30 years. The incidence of toxin B production in isolates from these patients was also significantly greater than in isolates acquired from the community in uncomplicated pharyngitis. These findings suggest a role for exotoxin in severe manifestations of Group A streptococcal disease in children.
Details
- Title: Subtitle
- Association of exotoxin-producing Group A streptococci and severe disease in children
- Creators
- KIRAN BELANIPATRICK SCHLIEVERTEDWARD KAPLANPATRICIA FERRIERI
- Resource Type
- Journal article
- Publication Details
- The Pediatric infectious disease journal, Vol.10(5), pp.351-354
- Publisher
- Williams & Wilkins
- DOI
- 10.1097/00006454-199105000-00001
- PMID
- 2067883
- ISSN
- 0891-3668
- eISSN
- 1532-0987
- Language
- English
- Date published
- 05/1991
- Academic Unit
- Microbiology and Immunology; Internal Medicine
- Record Identifier
- 9984002377602771
Metrics
24 Record Views