Journal article
Association of hospitalizations for asthma with seasonal and pandemic influenza
Respirology (Carlton, Vic.), Vol.19(1), pp.116-121
01/2014
DOI: 10.1111/resp.12165
PMCID: PMC3877191
PMID: 23931674
Abstract
Although influenza has been associated with asthma exacerbations, it is not clear the extent to which this association affects health care use in the United States. The first goal of this project was to determine whether, and to what extent, the incidence of asthma hospitalizations is associated with seasonal variation in influenza. Second, we used influenza trends (2000-2008) to help predict asthma admissions during the 2009 H1N1 influenza pandemic. We identified all hospitalizations between 1998 and 2008 in the Nationwide Inpatient Sample from the Healthcare Cost and Utilization Project during which a primary diagnosis of asthma was recorded. Separately, we identified all hospitalizations during which a diagnosis of influenza was recorded. We performed time series regression analyses to investigate the association of monthly asthma admissions with influenza incidence. Finally, we applied these time series regression models using 1998-2008 data, to forecast monthly asthma admissions during the 2009 influenza pandemic. Based on time series regression models, a strong, significant association exists between concurrent influenza activity and incidence of asthma hospitalizations (P-value < 0.0001). Use of influenza data to predict asthma admissions during the 2009 H1N1 pandemic improved the mean squared prediction error by 60.2%. Influenza activity in the population is significantly associated with asthma hospitalizations in the United States, and this association can be exploited to more accurately forecast asthma admissions. Our results suggest that improvements in influenza surveillance, prevention and treatment may decrease hospitalizations of asthma patients.
Details
- Title: Subtitle
- Association of hospitalizations for asthma with seasonal and pandemic influenza
- Creators
- Alicia K Gerke - Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USAMing YangFan TangEric D FosterJoseph E CavanaughPhilip M Polgreen
- Resource Type
- Journal article
- Publication Details
- Respirology (Carlton, Vic.), Vol.19(1), pp.116-121
- DOI
- 10.1111/resp.12165
- PMID
- 23931674
- PMCID
- PMC3877191
- NLM abbreviation
- Respirology
- ISSN
- 1440-1843
- eISSN
- 1440-1843
- Publisher
- Australia
- Grant note
- P30 ES005605 / NIEHS NIH HHS K01 AI75089 / NIAID NIH HHS K01 AI075089 / NIAID NIH HHS KL2 RR024980 / NCRR NIH HHS K23 HL114640 / NHLBI NIH HHS 1KL2RR024980 / NCRR NIH HHS
- Language
- English
- Date published
- 01/2014
- Academic Unit
- Statistics and Actuarial Science; Pulmonary, Critical Care, and Occupational Medicine; Infectious Diseases; Epidemiology; Biostatistics; College of Public Health; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9983985893602771
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