Journal article
Association of occupational exposures and chronic obstructive pulmonary disease morbidity
Journal of occupational and environmental medicine, Vol.65(7), pp.e443-e452
07/2023
DOI: 10.1097/JOM.0000000000002850
PMCID: PMC10330008
PMID: 36977360
Abstract
To determine whether aggregate measures of occupational exposures are associated with COPD outcomes in the SubPopulations and InteRmediate Outcome Measures In COPD Study cohort.
Individuals were assigned to six predetermined exposure hazard categories based on self-reported employment history. Multivariable regression, adjusted for age, gender, race, current smoking status, and smoking pack-years determined the association of such exposures to odds of COPD and morbidity measures. We compared these to the results of a single summary question regarding occupational exposure.
2772 individuals were included. Some exposure estimates, including 'gases and vapors' and 'dust and fumes' exposures resulted in associations with effect estimates over two times the estimated effect size when compared to a single summary question.
Use of occupational hazard categories can identify important associations with COPD morbidity while use of single point measures may underestimate important differences in health risks.
Details
- Title: Subtitle
- Association of occupational exposures and chronic obstructive pulmonary disease morbidity
- Creators
- Jennifer S RousPeter S J Lees - Johns Hopkins UniversityKirsten Koehler - Johns Hopkins UniversityJessie P Buckley - Johns Hopkins UniversityLesliam Quirós-Alcalá - Johns Hopkins UniversityMeiLan K Han - University of MichiganEric A Hoffman - University of IowaWassim Labaki - University of MichiganR Graham Barr - Columbia UniversityStephen P Peters - Wake Forest UniversityRobert Paine III - University of UtahCheryl Pirozzi - University of UtahChristopher B Cooper - University of California, Los AngelesMark T Dransfield - University of AlabamaAlejandro P ComellasRichard E Kanner - University of UtahM Bradley Drummond - University of North Carolina at Chapel HillNirupama Putcha - Johns Hopkins UniversityNadia N Hansel - Johns Hopkins UniversityLaura M Paulin - Department of Medicine, Dartmouth-Hitchcock Medical Center/Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire
- Resource Type
- Journal article
- Publication Details
- Journal of occupational and environmental medicine, Vol.65(7), pp.e443-e452
- DOI
- 10.1097/JOM.0000000000002850
- PMID
- 36977360
- PMCID
- PMC10330008
- NLM abbreviation
- J Occup Environ Med
- eISSN
- 1536-5948
- Language
- English
- Electronic publication date
- 03/27/2023
- Date published
- 07/2023
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Pulmonary, Critical Care, and Occupational Medicine; ICTS; Internal Medicine
- Record Identifier
- 9984381135702771
Metrics
20 Record Views