Journal article
Associations of Dairy Intake with CT Lung Density and Lung Function
Journal of the American College of Nutrition, Vol.29(5), pp.494-502
10/01/2010
DOI: 10.1080/07315724.2010.10719886
PMCID: PMC3616890
PMID: 21504976
Abstract
Objective: Dairy products contain vitamin D and other nutrients that may be beneficial for lung function, but they are also high in fats that may have mixed effects on lung function. However, the overall associations of dairy intake with lung density and lung function have not been studied.
Methods: We examined the cross-sectional relationships between dairy intake and computed tomography (CT) lung density and lung function in the Multi-Ethnic Study of Atherosclerosis (MESA). Total, low-fat, and high-fat dairy intakes were quantified from food frequency questionnaire responses of men and women who were ages 45-84 years and free of clinical cardiovascular disease. The MESA-Lung Study assessed CT lung density from cardiac CT imaging and prebronchodilator spirometry among 3965 MESA participants.
Results: Total dairy intake was inversely associated with apical-basilar difference in percent emphysema and positively associated with forced vital capacity (FVC) (the multivariate-adjusted mean difference between the highest and lowest quintiles of total dairy intake was -0.92 [p for trend = 0.04] for apical-basilar difference in percent emphysema and 72.0 mL [p = 0.01] for FVC). Greater low-fat dairy intake was associated with higher alpha (higher alpha values indicate less emphysema) and lower apical-basilar difference in percent emphysema (corresponding differences in alpha and apical-basilar difference in percent emphysema were 0.04 [p = 0.02] and 0.98 [p = 0.01] for low-fat dairy intake, respectively). High-fat dairy intake was not associated with lung density measures. Greater low- or high-fat dairy intake was not associated with higher forced expiratory volume in 1 second (FEV1). FVC, and FEV1/FVC.
Conclusions: Higher low-fat dairy intake but not high-fat dairy intake was associated with moderately improved CT lung density.
Details
- Title: Subtitle
- Associations of Dairy Intake with CT Lung Density and Lung Function
- Creators
- Rui Jiang - Royal College of PhysiciansDavid R. Jacobs - University of MinnesotaKa He - University of North Carolina at Chapel HillEric Hoffman - Roy J. and Lucille A. Carver College of MedicineJohn Hankinson - Hankinson Consulting, Valdosta, GeorgiaJennifer A. Nettleton - The University of Texas at AustinR. Graham Barr - Columbia University
- Resource Type
- Journal article
- Publication Details
- Journal of the American College of Nutrition, Vol.29(5), pp.494-502
- DOI
- 10.1080/07315724.2010.10719886
- PMID
- 21504976
- PMCID
- PMC3616890
- NLM abbreviation
- J Am Coll Nutr
- ISSN
- 0731-5724
- eISSN
- 1541-1087
- Publisher
- Taylor & Francis
- Number of pages
- 9
- Grant note
- N01HC095162 / DIVISION OF EPIDEMIOLOGY AND CLINICAL APPLICATIONS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI) K08AG030235 / NATIONAL INSTITUTE ON AGING; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA) R43HL095169 / NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) K08-AG030235; R01 HL-077612; R01-HL075476; N01-HC-095159; N01-HC-095165; N01-HC-095169 / US National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Language
- English
- Date published
- 10/01/2010
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Internal Medicine
- Record Identifier
- 9984318807802771
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