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Associations of Sleep Disturbance Symptoms with Health-Related Quality of Life in Parkinson’s Disease
Journal article   Peer reviewed

Associations of Sleep Disturbance Symptoms with Health-Related Quality of Life in Parkinson’s Disease

Alon Avidan, Ron D Hays, Natalie Diaz, Yvette Bordelon, Alexander W Thompson, Stefanie D Vassar and Barbara G Vickrey
The journal of neuropsychiatry and clinical neurosciences, Vol.25(4), pp.319-326
2013
DOI: 10.1176/appi.neuropsych.12070175
PMCID: PMC3960993
PMID: 24247858
url
http://doi.org/10.1176/appi.neuropsych.12070175View
Open Access

Abstract

We examined associations of different sleep disturbance symptoms with health-related quality of life (HRQOL) in 153 adults with Parkinson’s disease (PD). PD patients reported more snoring, sleep inadequacy, daytime somnolence, and sleep maintenance problems than the general population (p<0.001). Symptoms having the broadest and strongest unique associations with generic HRQOL (8 scales; 2 composites of SF-36) were daytime somnolence (5 scales; 1 composite), sleep initiation (8 scales; 2 composites), and awakening short of breath or with headache (6 scales; 2 composites) (p’s<0.05). Associations of selected sleep disturbance symptoms – some unanticipated – suggest that assessing specific symptoms is worthwhile in clinical care.
sleep disturbance health-related quality of life Parkinson’s disease

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