Journal article
Asymmetric Allylsilane Additions to Enantiopure N‐Acylhydrazones with Dual Activation by Fluoride and In(OTf)3
Angewandte Chemie International Edition, Vol.40(23), pp.4491-4493
12/03/2001
DOI: 10.1002/1521-3773(20011203)40:23<4491::AID-ANIE4491>3.0.CO;2-8
PMID: 12404456
Abstract
A mild, convenient, and stereoselective addition of allylsilanes to enantiopure N‐acylhydrazones occurs at room temperature upon complementary activation of both the allylsilane and the hydrazone (see scheme; OTf = trifluoromethanesulfonate). The reaction provides a new mode of acyclic stereocontrol for the asymmetric synthesis of homoallylic amines.
Details
- Title: Subtitle
- Asymmetric Allylsilane Additions to Enantiopure N‐Acylhydrazones with Dual Activation by Fluoride and In(OTf)3
- Creators
- Gregory K FriestadHui Ding
- Resource Type
- Journal article
- Publication Details
- Angewandte Chemie International Edition, Vol.40(23), pp.4491-4493
- Publisher
- WILEY‐VCH Verlag GmbH; Weinheim
- DOI
- 10.1002/1521-3773(20011203)40:23<4491::AID-ANIE4491>3.0.CO;2-8
- PMID
- 12404456
- ISSN
- 1433-7851
- eISSN
- 1521-3773
- Number of pages
- 3
- Language
- English
- Date published
- 12/03/2001
- Academic Unit
- Chemistry
- Record Identifier
- 9983985959402771
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