Journal article
Atypical Disseminated Zoster in a Patient With Unrecognized Severe Hypogammaglobulinemia
Annals of Internal Medicine: Clinical Cases, Vol.3(8), e231229
08/01/2024
DOI: 10.7326/aimcc.2023.1229
Abstract
A 74-year-old woman with history of chronic myeloid leukemia status post matched unrelated donor allogenic hematopoietic stem cell transplant in remission for 23 years was transferred to the intensive care unit with diffuse purpuric rash, progressive lethargy, shock, and multiorgan failure. She had presented to a local hospital a few days before admission with severe epigastric pain, radiating to her chest and back. Laboratory work-up revealed multiorgan failure, cytokine storm consistent with hemophagocytic lymphohistiocytosis, and severe hypogammaglobulinemia. Despite supportive management the patient's condition deteriorated, and she died. The skin biopsy and autopsy demonstrated disseminated varicella zoster with widespread leukocytoclastic vasculitis.
Details
- Title: Subtitle
- Atypical Disseminated Zoster in a Patient With Unrecognized Severe Hypogammaglobulinemia
- Creators
- Nathan Walton - University of ArizonaEyas Alzayadneh - University of IowaRobert Robinson - University of IowaRachael Stadlen - University of Iowa Hospitals and ClinicsRolando Sanchez - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Annals of Internal Medicine: Clinical Cases, Vol.3(8), e231229
- DOI
- 10.7326/aimcc.2023.1229
- ISSN
- 2767-7672
- eISSN
- 2767-7664
- Language
- English
- Date published
- 08/01/2024
- Academic Unit
- Pulmonary, Critical Care, and Occupational Medicine; Oral Pathology, Radiology and Medicine; Pathology; Internal Medicine
- Record Identifier
- 9984773415102771
Metrics
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