Journal article
Auditory Nerve Fiber Responses to Combined Acoustic and Electric Stimulation
Journal of the Association for Research in Otolaryngology, Vol.10(3), pp.425-445
09/2009
DOI: 10.1007/s10162-008-0154-7
PMCID: PMC3084386
PMID: 19205803
Abstract
Persons with a prosthesis implanted in a cochlea with residual acoustic sensitivity can, in some cases, achieve better speech perception with “hybrid” stimulation than with either acoustic or electric stimulation presented alone. Such improvements may involve “across auditory-nerve fiber” processes within central nuclei of the auditory system and within-fiber interactions at the level of the auditory nerve. Our study explored acoustic–electric interactions within feline auditory nerve fibers (ANFs) so as to address two goals. First, we sought to better understand recent results that showed non-monotonic recovery of the electrically evoked compound action potential (ECAP) following acoustic masking (Nourski et al.
2007
, Hear. Res. 232:87–103). We hypothesized that post-masking changes in ANF temporal properties and responsiveness (spike rate) accounted for the ECAP results. We also sought to describe, more broadly, the changes in ANF responses that result from prior acoustic stimulation. Five response properties—spike rate, latency, jitter, spike amplitude, and spontaneous activity—were examined. Post-masking reductions in spike rate, within-fiber jitter and across-fiber variance in latency were found, with the changes in temporal response properties limited to ANFs with high spontaneous rates. Thus, our results suggest how non-monotonic ECAP recovery occurs for ears with spontaneous activity, but cannot account for that pattern of recovery when there is no spontaneous activity, including the results from the presumably deafened ears used in the Nourski et al. (
2007
) study. Finally, during simultaneous (electric+acoustic) stimulation, the degree of electrically driven spike activity had a strong influence on spike rate, but did not affect spike jitter, which apparently was determined by the acoustic noise stimulus or spontaneous activity.
Details
- Title: Subtitle
- Auditory Nerve Fiber Responses to Combined Acoustic and Electric Stimulation
- Creators
- Charles A Miller - Department of Otolaryngology - Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA 52242 USAPaul J Abbas - Department of Otolaryngology - Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA 52242 USABarbara K Robinson - Department of Otolaryngology - Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA 52242 USAKirill V Nourski - Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, IA 52242 USAFawen Zhang - Department of Communication Sciences and Disorders, University of Cincinnati, Cincinnati, OH 45221 USAFuh-Cherng Jeng - School of Hearing, Speech and Language Sciences, Ohio University, Athens, OH 45701 USA
- Resource Type
- Journal article
- Publication Details
- Journal of the Association for Research in Otolaryngology, Vol.10(3), pp.425-445
- DOI
- 10.1007/s10162-008-0154-7
- PMID
- 19205803
- PMCID
- PMC3084386
- NLM abbreviation
- J Assoc Res Otolaryngol
- ISSN
- 1525-3961
- eISSN
- 1438-7573
- Publisher
- Springer-Verlag; New York
- Language
- English
- Date published
- 09/2009
- Academic Unit
- Communication Sciences and Disorders; Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
- Record Identifier
- 9984040272302771
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