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Autoimmune Reactivity in Inflammatory Bowel Disease
Journal article   Peer reviewed

Autoimmune Reactivity in Inflammatory Bowel Disease

David F Keren and James A Goeken
Clinics in laboratory medicine, Vol.17(3), pp.465-481
09/1997
DOI: 10.1016/S0272-2712(18)30206-3
PMID: 9316769

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Abstract

Inflammatory bowel disease remains a poorly understood chronic inflammatory condition of the bowel. No etiologic agents, or agreed upon pathogenesis is currently known. Recent findings that perinuclear antineutrophil cytoplasmic antibodies (P-ANCA) are present in the vast majority of patients with this disease have proven to be of use in epidemiologic studies. Its clinical use is currently being explored by several investigators.

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