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Autonomous artificial intelligence increases real-world specialist clinic productivity in a cluster-randomized trial
Journal article   Open access   Peer reviewed

Autonomous artificial intelligence increases real-world specialist clinic productivity in a cluster-randomized trial

Michael D. Abramoff, Noelle Whitestone, Jennifer L. Patnaik, Emily Rich, Munir Ahmed, Lutful Husain, Mohammad Yeadul Hassan, Md. Sajidul Huq Tanjil, Dena Weitzman, Tinglong Dai, …
NPJ digital medicine, Vol.6(1), 184
10/04/2023
DOI: 10.1038/s41746-023-00931-7
PMCID: PMC10550906
PMID: 37794054
url
https://doi.org/10.1038/s41746-023-00931-7View
Published (Version of record) Open Access

Abstract

Autonomous artificial intelligence (AI) promises to increase healthcare productivity, but real-world evidence is lacking. We developed a clinic productivity model to generate testable hypotheses and study design for a preregistered cluster-randomized clinical trial, in which we tested the hypothesis that a previously validated US FDA-authorized AI for diabetic eye exams increases clinic productivity (number of completed care encounters per hour per specialist physician) among patients with diabetes. Here we report that 105 clinic days are cluster randomized to either intervention (using AI diagnosis; 51 days; 494 patients) or control (not using AI diagnosis; 54 days; 499 patients). The prespecified primary endpoint is met: AI leads to 40% higher productivity (1.59 encounters/hour, 95% confidence interval [CI]: 1.37–1.80) than control (1.14 encounters/hour, 95% CI: 1.02–1.25), p  < 0.00; the secondary endpoint (productivity in all patients) is also met. Autonomous AI increases healthcare system productivity, which could potentially increase access and reduce health disparities. ClinicalTrials.gov NCT05182580.

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