Journal article
Autosomal recessive lamellar ichthyosis and acute lymphoblastic leukemia
European journal of human genetics : EJHG, Vol.4(2), pp.105-107
1996
DOI: 10.1159/000472178
PMID: 8744028
Abstract
Autosomal recessive lamellar ichthyosis (ARLI) is a congenital disorder of keratinization, the gene of which has been mapped to chromosome 14q11. This band is also the breakpoint in various chromosomal rearrangements in T cell acute lymphoblastic leukemia (ALL). We describe a patient with ARLI who developed ALL at the age of 2.5 years. High resolution banding showed no abnormality or rearrangement involving chromosome 14. To our knowledge, this is the first description of the occurrence of the two conditions in one patient.
Details
- Title: Subtitle
- Autosomal recessive lamellar ichthyosis and acute lymphoblastic leukemia
- Creators
- M al-Sheyyab - Department of Pediatrics, Jordan University of Science and Technology, Irbid, JordanH el ShantiD ToddA Shurman
- Resource Type
- Journal article
- Publication Details
- European journal of human genetics : EJHG, Vol.4(2), pp.105-107
- DOI
- 10.1159/000472178
- PMID
- 8744028
- ISSN
- 1018-4813
- eISSN
- 1476-5438
- Language
- English
- Date published
- 1996
- Academic Unit
- Stead Family Department of Pediatrics; Medical Genetics and Genomics
- Record Identifier
- 9984093215202771
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