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Axillary lymph node management in breast cancer with positive sentinel lymph node biopsy
Journal article

Axillary lymph node management in breast cancer with positive sentinel lymph node biopsy

Ioannis A. Voutsadakis and Silvana Spadafora
World journal of clinical oncology, Vol.6(1), pp.1-6
02/10/2015
DOI: 10.5306/wjco.v6.i1.1
PMCID: PMC4318745
PMID: 25667909

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Abstract

The surgical treatment of localized breast cancer has become progressively less aggressive over the years. The management of the axillary lymph nodes has been modified by the introduction of sentinel lymph node biopsy. Axillary dissection can be avoided in patients with sentinel lymph node negative biopsies. Based on randomized trials data, it has been proposed that no lymph node dissection should be carried out even in certain patients with sentinel lymph node positive biopsies. This commentary discusses the basis of such recommendations and cautions against a general omission of lymph node dissection in breast cancer patients with positive sentinel lymph node biopsies. Instead, an individualized approach based on axillary tumor burden and biology of the cancer should be considered.
Life Sciences & Biomedicine Oncology Science & Technology

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