Logo image
Azoospermia in a 46,xx/47,xxx phenotypic male
Journal article   Open access   Peer reviewed

Azoospermia in a 46,xx/47,xxx phenotypic male

Christopher S. Cooper and Jay I. Sandlow
Urology (Ridgewood, N.J.), Vol.48(6), pp.947-948
1996
DOI: 10.1016/S0090-4295(96)00321-4
PMID: 8973686
url
https://doi.org/10.1016/S0090-4295(96)00321-4View
Published (Version of record) Open Access

Abstract

We report the unique case of a 34-year-old 46,XX/47,XXX man with complete masculinization and azoospermia. Analysis of the patient's deoxyribonucleic acid failed to detect the azoospermia factor (AZF) region. Lack of germ cell elements on subsequent testicular biopsy illustrates the importance of the AZF region for spermatogenesis. Discussion concerning the genetics of testicular and germ cell formation is undertaken in the context of the patient presented.

Details

Metrics

Logo image