BSLIM: spectral localization by imaging with explicit B0 field inhomogeneity compensation

Ildar Khalidov; Dimitri Van De Ville; Mathews Jacob; François Lazeyras; Michael Unser

doi:10.1109/TMI.2007.897385

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BSLIM: spectral localization by imaging with explicit B0 field inhomogeneity compensation

Journal article

Open access

Peer reviewed

BSLIM: spectral localization by imaging with explicit B0 field inhomogeneity compensation

Ildar Khalidov, Dimitri Van De Ville, Mathews Jacob, François Lazeyras and Michael Unser

IEEE transactions on medical imaging, Vol.26(7), pp.990-1000

07/2007

DOI: 10.1109/TMI.2007.897385

PMID: 17649912

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Open Access

Abstract

Magnetic resonance spectroscopy imaging (MRSI) is an attractive tool for medical imaging. However, its practical use is often limited by the intrinsic low spatial resolution and long acquisition time. Spectral localization by imaging (SLIM) has been proposed as a non-Fourier reconstruction algorithm that incorporates spatial a priori information about spectroscopically uniform compartments. Unfortunately, the influence of the magnetic field inhomogeneity--in particular, the susceptibility effects at tissues' boundaries--undermines the validity of the compartmental model. Therefore, we propose BSLIM as an extension of SLIM with field inhomogeneity compensation. A B0-field inhomogeneity map, which can be acquired rapidly and at high resolution, is used by the new algorithm as additional a priori information. We show that the proposed method is distinct from the generalized SLIM (GSLIM) framework. Experimental results of a two-compartment phantom demonstrate the feasibility of the method and the importance of inhomogeneity compensation.

Reproducibility of Results

Algorithms

Magnetic Resonance Imaging - instrumentation

Magnetic Resonance Spectroscopy - methods

Image Interpretation, Computer-Assisted - methods

Sensitivity and Specificity

Imaging, Three-Dimensional - methods

Magnetic Resonance Imaging - methods

Image Enhancement - methods

Magnetic Resonance Spectroscopy - instrumentation

Phantoms, Imaging

Details

Title: Subtitle: BSLIM: spectral localization by imaging with explicit B0 field inhomogeneity compensation
Creators: Ildar Khalidov - Biomedical Imaging Group, EPFL, Lausanne, Switzerland. ildar.khalidov@epfl.ch
Dimitri Van De Ville
Mathews Jacob
François Lazeyras
Michael Unser
Resource Type: Journal article
Publication Details: IEEE transactions on medical imaging, Vol.26(7), pp.990-1000
DOI: 10.1109/TMI.2007.897385
PMID: 17649912
NLM abbreviation: IEEE Trans Med Imaging
ISSN: 0278-0062
eISSN: 1558-254X
Publisher: Institute of Electrical and Electronics Engineers; United States
Language: English
Date published: 07/2007
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Radiology; Electrical and Computer Engineering; Iowa Neuroscience Institute; Radiation Oncology
Record Identifier: 9984070418902771

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