Bacterial Vaginosis and the Natural History of Human Papillomavirus

Caroline C. King; Denise J. Jamieson; Jeffrey Wiener; Susan Cu-Uvin; Robert S. Klein; Anne M. Rompalo; Keerti V. Shah; Jack D. Sobel

doi:10.1155/2011/319460

Back

Bacterial Vaginosis and the Natural History of Human Papillomavirus

Journal article

Open access

Peer reviewed

Bacterial Vaginosis and the Natural History of Human Papillomavirus

Caroline C. King, Denise J. Jamieson, Jeffrey Wiener, Susan Cu-Uvin, Robert S. Klein, Anne M. Rompalo, Keerti V. Shah and Jack D. Sobel

Infectious diseases in obstetrics and gynecology, Vol.2011, pp.1-8

2011

DOI: 10.1155/2011/319460

PMCID: PMC3159014

PMID: 21869857

Files and links (1)

url

https://doi.org/10.1155/2011/319460View

Published (Version of record) Open Access

Abstract

Objective . To evaluate associations between common vaginal infections and human papillomavirus (HPV). Study Design . Data from up to 15 visits on 756 HIV-infected women and 380 high-risk HIV-uninfected women enrolled in the HIV Epidemiology Research Study (HERS) were evaluated for associations of bacterial vaginosis, trichomoniasis, and vaginal Candida colonization with prevalent HPV, incident HPV, and clearance of HPV in multivariate analysis. Results . Bacterial vaginosis (BV) was associated with increased odds for prevalent (aOR = 1.14, 95% CI: 1.04, 1.26) and incident (aOR = 1.24, 95% CI: 1.04, 1.47) HPV and with delayed clearance of infection (aHR = 0.84, 95% CI: 0.72, 0.97). Whereas BV at the preceding or current visit was associated with incident HPV, in an alternate model for the outcome of incident BV, HPV at the current, but not preceding, visit was associated with incident BV. Conclusion . These findings underscore the importance of prevention and successful treatment of bacterial vaginosis.

Details

Title: Subtitle: Bacterial Vaginosis and the Natural History of Human Papillomavirus
Creators: Caroline C. King - Centers for Disease Control and Prevention
Denise J. Jamieson - Centers for Disease Control and Prevention
Jeffrey Wiener - Centers for Disease Control and Prevention
Susan Cu-Uvin - Brown University
Robert S. Klein - Icahn School of Medicine at Mount Sinai
Anne M. Rompalo - Johns Hopkins Medicine
Keerti V. Shah - Johns Hopkins University
Jack D. Sobel - Wayne State University
Resource Type: Journal article
Publication Details: Infectious diseases in obstetrics and gynecology, Vol.2011, pp.1-8
DOI: 10.1155/2011/319460
PMID: 21869857
PMCID: PMC3159014
NLM abbreviation: Infect Dis Obstet Gynecol
ISSN: 1064-7449
eISSN: 1098-0997
Grant note: DOI: 10.13039/100000030, name: Centers for Disease Control and Prevention, award: U64/CCU106795, U64/CCU206798, U64/CCU306802, U64/CCU506831
Language: English
Date published: 2011
Academic Unit: Obstetrics and Gynecology; VPMA - Administration
Record Identifier: 9984446437002771

Metrics

15 Record Views