Logo image
Bacteriophage association of streptococcal pyrogenic exotoxin type C
Journal article   Open access   Peer reviewed

Bacteriophage association of streptococcal pyrogenic exotoxin type C

S C Goshorn and P M Schlievert
Journal of bacteriology, Vol.171(6), pp.3068-3073
06/1989
DOI: 10.1128/jb.171.6.3068-3073.1989
PMCID: PMC210016
PMID: 2566595
url
https://doi.org/10.1128/jb.171.6.3068-3073.1989View
Published (Version of record) Open Access

Abstract

A gene encoding streptococcal pyrogenic exotoxin type C (SPE C) was isolated from bacteriophage DNA derived from Streptococcus pyogenes CS112. The gene, designated speC2, was shown to reside near the phage attachment site of phage CS112. A restriction endonuclease map of the CS112 phage was generated, and the location and orientation of the speC2 gene were determined. Hybridization analyses of eight SPE C-producing strains revealed restriction fragment length polymorphism of the speC gene-containing DNA fragments and further showed that each speC was linked to a common CS112 phage-derived DNA fragment.
Streptococcus pyogenes - genetics Nucleic Acid Hybridization Polymorphism, Restriction Fragment Length Genes Immunodiffusion Cloning, Molecular Exotoxins - genetics Genes, Viral Bacteriophages - genetics Bacterial Toxins - genetics DNA, Viral - genetics Restriction Mapping

Details

Metrics

Logo image