Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study

Anne P Cameron; Christina Lewicky-Gaupp; Abigail R Smith; Brian T Helfand; John L Gore; J. Quentin Clemens; Claire C Yang; Nazema Y Siddiqui; H. Henry Lai; James W Griffith; Victor P Andreev; Gang Liu; Kevin Weinfurt; Cindy L Amundsen; Catherine S Bradley; John W Kusek; Ziya Kirkali; Symptoms of Lower Urinary Tract Dysfunction Research Network Study Group

doi:10.1016/j.juro.2017.10.035

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Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study

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Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study

Anne P Cameron, Christina Lewicky-Gaupp, Abigail R Smith, Brian T Helfand, John L Gore, J. Quentin Clemens, Claire C Yang, Nazema Y Siddiqui, H. Henry Lai, James W Griffith, …

The Journal of Urology, Vol.199(4), pp.1023-1031

04/2018

DOI: 10.1016/j.juro.2017.10.035

PMID: 29111381

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Abstract

We described and compared the frequency and type of lower urinary tract symptoms reported by men and women at the time that they were recruited from urology and urogynecology clinics into the Symptoms of Lower Urinary Tract Dysfunction Research Network multicenter, prospective, observational cohort study. At 6 research sites treatment seeking men and women were enrolled who reported any lower urinary tract symptoms at a frequency more than rarely during the last month on the LUTS (Lower Urinary Tract Symptoms) Tool. At baseline the study participants underwent a standardized clinical evaluation and completed validated questionnaires. Urological tests were performed, including pelvic/rectal examination, post-void residual urine measurement and urinalysis. A total of 545 women and 519 men were enrolled in the study. Mean ± SD age was 58.8 ± 14.1 years. At baseline nocturia, frequency and a sensation of incomplete emptying were similar in men and women but men experienced more voiding symptoms (90% vs 85%, p = 0.007) and women reported more urgency (85% vs 66%, p <0.001). Women also reported more of any type of urinary incontinence than men (82% vs 51% p <0.001), which was mixed incontinence in 57%. Only 1% of men reported stress incontinence but they had other urinary incontinence, including post-void dribbling in 44% and urgency incontinence in 46%. Older participants had higher odds of reporting symptoms of nocturia and urgency. In this large, treatment seeking cohort of men and women lower urinary tract symptoms varied widely by gender and age. Men reported more voiding symptoms and nonstress or urgency urinary incontinence while women reported more incontinence overall and urgency. Older participants had greater odds of urgency and nocturia.

lower urinary tract symptoms

overactive

urinary incontinence

urinary bladder

men's health

women's health

Details

Title: Subtitle: Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study
Creators: Anne P Cameron - Michigan Medicine Urology Clinic, University of Michigan, Ann Arbor, Michigan
Christina Lewicky-Gaupp - Northwestern University Feinberg School of Medicine, Chicago, Illinois
Abigail R Smith - Arbor Research Collaborative for Health, Ann Arbor, Michigan
Brian T Helfand - NorthShore University HealthSystem, Glenview, Illinois
John L Gore - Urology Clinic, University of Washington Medical Center, Seattle, Washington
J. Quentin Clemens - Michigan Medicine Urology Clinic, University of Michigan, Ann Arbor, Michigan
Claire C Yang - Urology Clinic, University of Washington Medical Center, Seattle, Washington
Nazema Y Siddiqui - Division of Urogynecology and Reconstructive Surgery, Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina
H. Henry Lai - Washington University School of Medicine in St. Louis, St. Louis, Missouri
James W Griffith - Northwestern University Feinberg School of Medicine, Chicago, Illinois
Victor P Andreev - Arbor Research Collaborative for Health, Ann Arbor, Michigan
Gang Liu - Arbor Research Collaborative for Health, Ann Arbor, Michigan
Kevin Weinfurt - Duke University Medical Center, Durham, North Carolina
Cindy L Amundsen - Division of Urogynecology and Reconstructive Surgery, Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina
Catherine S Bradley - Department of Obstetrics and Gynecology, University of Iowa Carver College of Medicine, Iowa City, Iowa
John W Kusek - National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland
Ziya Kirkali - National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland
Symptoms of Lower Urinary Tract Dysfunction Research Network Study Group
Resource Type: Journal article
Publication Details: The Journal of Urology, Vol.199(4), pp.1023-1031
DOI: 10.1016/j.juro.2017.10.035
PMID: 29111381
NLM abbreviation: J Urol
ISSN: 0022-5347
eISSN: 1527-3792
Publisher: Elsevier Inc
Language: English
Date published: 04/2018
Academic Unit: Epidemiology; Obstetrics and Gynecology; Urology
Record Identifier: 9983930274902771

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