Journal article
Becker muscular dystrophy recombinant DNA studies in identical twins
Muscle & nerve, Vol.11(4), pp.287-290
04/1988
DOI: 10.1002/mus.880110402
PMID: 3398874
Abstract
Two identical twins with becker Muscular Dystrophy are reported. Both twins had the same red cell types for ABO, Rh, CDE, MNSs, Kelly, Lewis, Duffy, and Kidd. HLA typing detected the same antigens in both twins: A1, A26, B8, B17, DR3, DR7. Family history was negative. The twin patients showed identical haplotypes that were different from the haplotypes of the normal male members of the family. The sister of the twins showed a recombinant X chromosome. The informative haplotype with respect to the gene of BMD, present in the twins, was ascertained in their mother as well. Our findings strongly suggest that a mutation has occurred either in the mother or in the twins. Copyright © 1988 John Wiley & Sons, Inc.
Details
- Title: Subtitle
- Becker muscular dystrophy recombinant DNA studies in identical twins
- Creators
- Victor Ionasescu - University of IowaRebecca Ionasescu - University of Iowa Hospitals and ClinicsCharles Searby - University of IowaTrudy Burns - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Muscle & nerve, Vol.11(4), pp.287-290
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company
- DOI
- 10.1002/mus.880110402
- PMID
- 3398874
- ISSN
- 0148-639X
- eISSN
- 1097-4598
- Number of pages
- 4
- Language
- English
- Date published
- 04/1988
- Academic Unit
- Stead Family Department of Pediatrics; Epidemiology; Fraternal Order of Eagles Diabetes Research Center
- Record Identifier
- 9984363605702771
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