Journal article
Benefits of acupuncture for diabetic gastroparesis: a comparative preliminary study
Acupuncture in medicine : journal of the British Medical Acupuncture Society, Vol.32(2), pp.139-145
04/2014
DOI: 10.1136/acupmed-2013-010465
PMID: 24323633
Abstract
Objectives The aim of this preliminary study was to compare the effectiveness of domperidone and acupuncture for the management of diabetic gastroparesis. Methods This was a preliminary, prospective non-randomised, unblinded case-crossover study conducted in patients with longstanding, uncontrolled diabetes mellitus and gastroparesis. All patients received domperidone (20 mg four times a day) for 12 weeks, followed by a 2–3 week washout period, and then biweekly acupuncture treatments for 8 weeks. Gastric emptying rate, glucose and glycated haemoglobin (HbA1C) levels were measured at start and end of each treatment period. At each of these timepoints patients completed the Gastroparesis Cardinal Symptom Index (GCSI), the Satisfaction with Life Scale (SWLS), and the Short-Form 36 Health Survey Update (SF-36). Results The trial was curtailed after only eight participants could be recruited in 3 years. The mean age of patients was 57.1±9.9 years, the male:female ratio was 1:7 and mean body mass index (kg/m2) was 25.2±1.2. There was no change in any of the outcome parameters after treatment with domperidone. Acupuncture was associated with a decrease in scores for almost all cardinal symptoms of the GCSI, as well as in increased total score on the SWLS (p=0.002) and the social functioning domain of the SF-36 (p=0.054). Acupuncture did not lead to an improvement in gastric emptying, or glucose control from baseline. Conclusions Acupuncture treatment may lead to symptomatic improvement in patients with diabetic gastroparesis. Within the limitations of this preliminary, non-randomised and unblinded study, it appears that this effect may be due to non-specific mechanisms.
Details
- Title: Subtitle
- Benefits of acupuncture for diabetic gastroparesis: a comparative preliminary study
- Creators
- Netanella Danielli Miller - Technion – Israel Institute of TechnologyElad Schiff - Bnai Zion Medical CenterEran Ben-Arye - Technion – Israel Institute of TechnologyJoelle Singer - Rabin Medical CenterTsachi Tsadok Perets - Tel Aviv UniversityShlomit Flaut - Rabin Medical CenterNadav Sahar - Rabin Medical CenterYaron Niv - Rabin Medical CenterRam Dickman - Rabin Medical Center
- Resource Type
- Journal article
- Publication Details
- Acupuncture in medicine : journal of the British Medical Acupuncture Society, Vol.32(2), pp.139-145
- DOI
- 10.1136/acupmed-2013-010465
- PMID
- 24323633
- ISSN
- 0964-5284
- eISSN
- 1759-9873
- Language
- English
- Date published
- 04/2014
- Academic Unit
- Gastroenterology and Hepatology; Internal Medicine
- Record Identifier
- 9984359572402771
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