Journal article
Beta power in the EEG of alcoholics
Biological psychiatry (1969), Vol.52(8), pp.831-842
2002
DOI: 10.1016/S0006-3223(02)01362-8
PMID: 12372655
Abstract
In this study, the magnitude and spatial distribution of beta power in the resting electroencephalogram (EEG) were examined to address the possibility of an excitation–inhibition imbalance in the central nervous system of alcoholics.
Log transformed absolute power in the Beta 1 (12.5–16 Hz), Beta 2 (16.5–20 Hz), and Beta 3 (20.5–28 Hz) bands in the eyes-closed EEG of 307 alcohol-dependent subjects and 307 unaffected age- and gender-matched control subjects were compared using a multivariate repeated measures design. Effect of gender, age, and drinking variables was examined separately.
Increased Beta 1 (12.5–16 Hz) and Beta 2 (16.5–20 Hz) absolute power was observed in alcohol-dependent subjects at all loci over the scalp. The increase was most prominent in the central region. Increased Beta 3 (20.5–28 Hz) power was frontal in the alcoholics. Age and clinical variables did not influence the increase. Male alcoholics had significantly higher beta power in all three bands. In female alcoholics the increase did not reach statistical significance.
Beta power in all three bands of resting EEG is elevated in alcoholics. This feature is more prominent in male alcoholics. The increased beta power in the resting EEG may be an electrophysiological index of the imbalance in the excitation–inhibition homeostasis in the cortex.
Details
- Title: Subtitle
- Beta power in the EEG of alcoholics
- Creators
- Madhavi Rangaswamy - Department of Psychiatry, State University of New York, Health Science Center at Brooklyn, (MR, BP, DBC, KMW, KAJ, HB) Brooklyn, New York, USABernice Porjesz - Department of Psychiatry, State University of New York, Health Science Center at Brooklyn, (MR, BP, DBC, KMW, KAJ, HB) Brooklyn, New York, USADavid B Chorlian - Department of Psychiatry, State University of New York, Health Science Center at Brooklyn, (MR, BP, DBC, KMW, KAJ, HB) Brooklyn, New York, USAKongming Wang - Department of Psychiatry, State University of New York, Health Science Center at Brooklyn, (MR, BP, DBC, KMW, KAJ, HB) Brooklyn, New York, USAKevin A Jones - Department of Psychiatry, State University of New York, Health Science Center at Brooklyn, (MR, BP, DBC, KMW, KAJ, HB) Brooklyn, New York, USALance O Bauer - Department of Psychiatry, University of Connecticut Health Center, (LOB) Farmington, Connecticut, USAJohn Rohrbaugh - Division of Family Studies, Washington University, (JR) St. Louis, Missouri, USASean J O’Connor - Department of Psychiatry, Institute of Psychiatric Research, Indiana University Medical Center, (SJO) Indianapolis, Indiana, USASamuel Kuperman - Division of Child Psychiatry, University of Iowa Hospitals, (SK) Iowa City, Iowa, USATheodore Reich - Department of Psychiatry, Washington University, School of Medicine, (TR) St. Louis, Missouri, USAHenri Begleiter - Department of Psychiatry, State University of New York, Health Science Center at Brooklyn, (MR, BP, DBC, KMW, KAJ, HB) Brooklyn, New York, USA
- Resource Type
- Journal article
- Publication Details
- Biological psychiatry (1969), Vol.52(8), pp.831-842
- Publisher
- Elsevier Inc
- DOI
- 10.1016/S0006-3223(02)01362-8
- PMID
- 12372655
- ISSN
- 0006-3223
- eISSN
- 1873-2402
- Language
- English
- Date published
- 2002
- Academic Unit
- Psychiatry; Stead Family Department of Pediatrics
- Record Identifier
- 9984003919302771
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