Between-module functional connectivity of the salient ventral attention network and dorsal attention network is associated with motor inhibition

Howard Muchen Hsu; Zai-Fu Yao; Kai Hwang; Shulan Hsieh

doi:10.1371/journal.pone.0242985

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Between-module functional connectivity of the salient ventral attention network and dorsal attention network is associated with motor inhibition

Journal article

Open access

Peer reviewed

Between-module functional connectivity of the salient ventral attention network and dorsal attention network is associated with motor inhibition

Howard Muchen Hsu, Zai-Fu Yao, Kai Hwang and Shulan Hsieh

PloS one, Vol.15(12), pp.e0242985-e0242985

2020

DOI: 10.1371/journal.pone.0242985

PMID: 33270664

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Abstract

The ability to inhibit motor response is crucial for daily activities. However, whether brain networks connecting spatially distinct brain regions can explain individual differences in motor inhibition is not known. Therefore, we took a graph-theoretic perspective to examine the relationship between the properties of topological organization in functional brain networks and motor inhibition. We analyzed data from 141 healthy adults aged 20 to 78, who underwent resting-state functional magnetic resonance imaging and performed a stop-signal task along with neuropsychological assessments outside the scanner. The graph-theoretic properties of 17 functional brain networks were estimated, including within-network connectivity and between-network connectivity. We employed multiple linear regression to examine how these graph-theoretical properties were associated with motor inhibition. The results showed that between-network connectivity of the salient ventral attention network and dorsal attention network explained the highest and second highest variance of individual differences in motor inhibition. In addition, we also found those two networks span over brain regions in the frontal-cingulate-parietal network, suggesting that these network interactions are also important to motor inhibition.

Motor Activity - physiology

Brain - diagnostic imaging

Nerve Net - diagnostic imaging

Humans

Middle Aged

Male

Brain - physiology

Nerve Net - physiology

Young Adult

Attention - physiology

Magnetic Resonance Imaging

Image Processing, Computer-Assisted

Aged, 80 and over

Brain Mapping

Adult

Female

Aged

Details

Title: Subtitle: Between-module functional connectivity of the salient ventral attention network and dorsal attention network is associated with motor inhibition
Creators: Howard Muchen Hsu - Department of Psychology, National Cheng Kung University, Tainan, Taiwan
Zai-Fu Yao - Department of Psychology, Brain and Cognition, University of Amsterdam, Amsterdam, The Netherlands
Kai Hwang - Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, United States of America
Shulan Hsieh - Department and Institute of Public Health, National Cheng Kung University, Tainan, Taiwan
Resource Type: Journal article
Publication Details: PloS one, Vol.15(12), pp.e0242985-e0242985
DOI: 10.1371/journal.pone.0242985
PMID: 33270664
NLM abbreviation: PLoS One
ISSN: 1932-6203
eISSN: 1932-6203
Publisher: Public Library of Science; United States
Grant note: DOI: 10.13039/501100004663, name: Ministry of Science and Technology, Taiwan, award: MOST 104-2410-H-006-021-MY2, MOST 106-2410-H-006-031-MY2; DOI: 10.13039/501100004663, name: Ministry of Science and Technology, Taiwan, award: MOST 108-2410-H-006-038-MY3; DOI: 10.13039/501100004663, name: Ministry of Science and Technology, Taiwan, award: MOST 108-2321-B-006-022-MY2
Language: English
Date published: 2020
Academic Unit: Psychiatry; Psychological and Brain Sciences; Iowa Neuroscience Institute
Record Identifier: 9984070149402771

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