Journal article
Beyond identification: emerging and future uses for MALDI-TOF mass spectrometry in the clinical microbiology laboratory
Clinics in laboratory medicine, Vol.33(3), pp.611-628
09/2013
DOI: 10.1016/j.cll.2013.03.013
PMID: 23931841
Abstract
The routine use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has revolutionized microorganism identification in the clinical microbiology laboratory. Building from these now common microorganism identification strategies, this review explores future clinical applications of MALDI-TOF MS. This includes practical approaches for laboratorians interested in implementing direct identification processing methods for MALDI-TOF detection of microbes in bloodstream infection (BSI) and urinary tract infection (UTI), as well as, post-analytical approaches for classifying MALDI-TOF spectral data to detect characteristics other and species-level identification (e.g. strain-level classification, typing, and resistance mechanisms).
Details
- Title: Subtitle
- Beyond identification: emerging and future uses for MALDI-TOF mass spectrometry in the clinical microbiology laboratory
- Creators
- Mari L DeMarco - Department of Pathology and Laboratory Medicine, University of British Columbia, St. Paul's Hospital, Vancouver, BC, V6Z 1Y6, CanadaBradley A Ford
- Resource Type
- Journal article
- Publication Details
- Clinics in laboratory medicine, Vol.33(3), pp.611-628
- Publisher
- United States
- DOI
- 10.1016/j.cll.2013.03.013
- PMID
- 23931841
- ISSN
- 0272-2712
- eISSN
- 1557-9832
- Language
- English
- Date published
- 09/2013
- Academic Unit
- Pathology
- Record Identifier
- 9984047704202771
Metrics
50 Record Views