Journal article
Bidirectional associations of accelerometer measured sedentary behavior and physical activity with knee pain, stiffness, and physical function: The CARDIA study
Preventive medicine reports, Vol.22, pp.101348-101348
06/01/2021
DOI: 10.1016/j.pmedr.2021.101348
PMCID: PMC8005813
PMID: 33816086
Abstract
The objective was to examine bidirectional associations of accelerometer estimated sedentary time and physical activity with reported knee symptoms. Participants were 2,034 adults (mean age 45.3 +/- 3.6 years, 58.7% female) from CARDIA. Generalized estimating equations for logistic regression and linear mixed regression models examined associations of accelerometer estimated sedentary time, light-intensity physical activity (LPA), and moderate-to-vigorous intensity physical activity (MVPA) at baseline (2005-06) with knee discomfort, pain, stiffness, and physical function (yes/no and continuous scores from short-form WOMAC function scale) at the 5-and 10-year follow-up exams. Linear regression models examined associations between knee symptoms at the 5-year follow-up with accelerometer estimates at the 10-year follow-up. Models were adjusted for confounders; individuals with comorbidities were excluded in sensitivity analyses. A 30 min/day increment in sedentary time at baseline was associated with lower odds of knee symptoms at the 5- and 10-year follow-up (OR: 0.95, 95% CI range: 0.92-0.98), while LPA and MVPA were associated with greater odds of knee symptoms (LPA OR range: 1.04-1.05, 95% CI range: 1.01-1.09; MVPA OR range: 1.17-1.19, 95% CI range: 1.06-1.32). Report of knee symptoms at the 5-year follow-up was associated with 13.52-17.51 (95% CI range: 29.90, 0.56) fewer minutes/day of sedentary time and 14.58-17.51 (95% CI range: 2.48, 29.38) more minutes/day of LPA at the 10-year follow-up, compared to those reporting no symptoms. Many associations were no longer statistically significant when excluding individuals with comorbidities. Findings support a bidirectional association of accelerometer estimated sedentary time and physical activity with knee symptoms across midlife.
Details
- Title: Subtitle
- Bidirectional associations of accelerometer measured sedentary behavior and physical activity with knee pain, stiffness, and physical function: The CARDIA study
- Creators
- Kara M Whitaker - University of IowaKelley Pettee Gabriel - University of Alabama at BirminghamDeepika Laddu - University of Illinois ChicagoDaniel K White - University of DelawareStephen Sidney - Kaiser PermanenteBarbara Sternfeld - Kaiser PermanenteCora E Lewis - University of Alabama at BirminghamDavid R Jacobs - University of Minnesota
- Resource Type
- Journal article
- Publication Details
- Preventive medicine reports, Vol.22, pp.101348-101348
- DOI
- 10.1016/j.pmedr.2021.101348
- PMID
- 33816086
- PMCID
- PMC8005813
- NLM abbreviation
- Prev Med Rep
- ISSN
- 2211-3355
- eISSN
- 2211-3355
- Publisher
- ELSEVIER
- Number of pages
- 9
- Grant note
- National Heart, Lung, and Blood Institute (NHLBI); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) HHSN268201800003I / Northwestern University HHSN268201800004I / Kaiser Foundation Research Institute HHSN268201800005I; HHSN268201800007I / University of Alabama at Birmingham R01 HL078972; R56 HL125423; K01HL148503 / NHLBI; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) HHSN268201800006I / University of Minnesota; University of Minnesota System
- Language
- English
- Date published
- 06/01/2021
- Academic Unit
- Epidemiology; Health, Sport, and Human Physiology
- Record Identifier
- 9984245666602771
Metrics
12 Record Views