Bilateral herpes simplex keratitis with unilateral secondary bacterial keratitis and corneal perforation in a patient with pityriasis rubra pilaris

Anna S Kitzmann; Kenneth M Goins; Nasreen A Syed; Michael D Wagoner

doi:10.1097/ICO.0b013e318180f0a8

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Bilateral herpes simplex keratitis with unilateral secondary bacterial keratitis and corneal perforation in a patient with pityriasis rubra pilaris

Journal article

Peer reviewed

Bilateral herpes simplex keratitis with unilateral secondary bacterial keratitis and corneal perforation in a patient with pityriasis rubra pilaris

Anna S Kitzmann, Kenneth M Goins, Nasreen A Syed and Michael D Wagoner

Cornea, Vol.27(10), pp.1212-1214

12/2008

DOI: 10.1097/ICO.0b013e318180f0a8

PMID: 19034146

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Abstract

To report a case of bilateral herpes simplex keratitis with unilateral secondary bacterial keratitis resulting in corneal perforation in a patient with pityriasis rubra pilaris. Case report. A 77-year-old female with pityriasis rubra pilaris was referred for a perforated corneal ulcer of the left eye. Cultures were positive in both eyes for Herpes simplex and in the left eye for Pseudomonas fluorescens and Staphylococcus aureus A microbiological cure was obtained with a combination of tectonic keratoplasty, fortified topical antibiotics, and systemic acyclovir. Pityriasis rubra pilaris is a rare, inflammatory dermatologic disease that may predispose patients to bilateral Herpes simplex keratitis, secondary bacterial superinfection, and a tendency toward rapid stromal ulceration with risk of perforation.

Corneal Transplantation

Keratitis - complications

Administration, Oral

Keratitis - microbiology

Humans

Keratitis, Herpetic - complications

Pseudomonas fluorescens

Cefazolin - administration & dosage

Antiviral Agents - administration & dosage

Staphylococcal Infections

Bacterial Infections

Ceftazidime - administration & dosage

Corneal Ulcer - etiology

Keratitis, Herpetic - therapy

Female

Aged

Pseudomonas Infections

Administration, Topical

Anti-Bacterial Agents - administration & dosage

Pityriasis Rubra Pilaris - complications

Acyclovir - administration & dosage

Keratitis - therapy

Details

Title: Subtitle: Bilateral herpes simplex keratitis with unilateral secondary bacterial keratitis and corneal perforation in a patient with pityriasis rubra pilaris
Creators: Anna S Kitzmann - Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
Kenneth M Goins
Nasreen A Syed
Michael D Wagoner
Resource Type: Journal article
Publication Details: Cornea, Vol.27(10), pp.1212-1214
Publisher: United States
DOI: 10.1097/ICO.0b013e318180f0a8
PMID: 19034146
ISSN: 0277-3740
eISSN: 1536-4798
Language: English
Date published: 12/2008
Academic Unit: Pathology; Ophthalmology and Visual Sciences
Record Identifier: 9983979912102771

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