Journal article
Bioavailable Testosterone as a Correlate of Cognition, Psychological Status, Quality of Life, and Sexual Function in Aging Males: Implications for Testosterone Replacement Therapy
Annals of clinical psychiatry, Vol.13(2), pp.75-80
2001
DOI: 10.3109/10401230109148951
PMID: 11534928
Abstract
Abstract
Andropause is a syndrome described in aging males, is composed of a constellation of physical, sexual, and emotional symptoms, and is thought to be related to declining concentrations of serum testosterone. Numerous studies of testosterone replacement therapy in elderly hypogo-nadal males have documented the physical benefits of such treatment, but have failed to assess cognition, psychological functioning, and quality of life. Male outpatients greater or equal to 55 years of age completed cognitive, psychological, sexual, and quality of life assessments. A serum sample was provided for bioavailable testosterone assay. The associations between bioavailable testosterone concentrations and neuropsychological testing were assessed using Spearman rank correlation. Overall, bioavailable testosterone was not an important determinant of cognitive, psychological, or sexual functioning or of quality of life. The implications for future studies involving testosterone replacement therapy are discussed.
Details
- Title: Subtitle
- Bioavailable Testosterone as a Correlate of Cognition, Psychological Status, Quality of Life, and Sexual Function in Aging Males: Implications for Testosterone Replacement Therapy
- Creators
- Paul J Perry - Clinical and Administrative Pharmacy Division, College of Pharmacy, University of Iowa, Iowa City, IowaBrian C Lund - Clinical and Administrative Pharmacy Division, College of Pharmacy, University of Iowa, Iowa City, IowaStephan Arndt - Department of Psychiatry, College of Medicine, University of Iowa, Iowa City, IowaTimothy Holman - Clinical and Administrative Pharmacy Division, College of Pharmacy, University of Iowa, Iowa City, IowaKristine A Bever-stille - Clinical and Administrative Pharmacy Division, College of Pharmacy, University of Iowa, Iowa City, IowaJane Paulsen - Department of Psychiatry, College of Medicine, University of Iowa, Iowa City, IowaLaurence M Demers - Department of Pathology, Penn State University College of Medicine, Hershey, Pennsylvania
- Resource Type
- Journal article
- Publication Details
- Annals of clinical psychiatry, Vol.13(2), pp.75-80
- DOI
- 10.3109/10401230109148951
- PMID
- 11534928
- NLM abbreviation
- Ann Clin Psychiatry
- ISSN
- 1040-1237
- eISSN
- 1547-3325
- Publisher
- Informa UK Ltd
- Language
- English
- Date published
- 2001
- Academic Unit
- Pharmacy; Psychiatry; Epidemiology; Psychological and Brain Sciences; Biostatistics; Nursing; Injury Prevention Research Center
- Record Identifier
- 9984083255202771
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