Journal article
Biobehavioral Influences on Cancer Progression
Immunology and allergy clinics of North America, Vol.31(1), pp.109-132
2011
DOI: 10.1016/j.iac.2010.09.001
PMCID: PMC3011980
PMID: 21094927
Abstract
This review focuses on the contributions of stress-related behavioral factors to cancer growth and metastasis and the biobehavioral mechanisms underlying these relationships. Behavioral factors that are important in modulation of the stress response and the pivotal role of neuroendocrine regulation in the downstream alteration of physiologic pathways relevant to cancer control, including the cellular immune response, inflammation, and tumor angiogenesis, invasion, and cell signaling pathways are described. Consequences for cancer progression and metastasis, as well as quality of life, are delineated. Behavioral and pharmacologic interventions with the potential to alter these biobehavioral pathways for patients with cancer are discussed.
Details
- Title: Subtitle
- Biobehavioral Influences on Cancer Progression
- Creators
- Erin S Costanzo - Department of Psychiatry, Carbone Comprehensive Cancer Center, University of Wisconsin-Madison, 6001 Research Park Boulevard, Madison, WI 53719, USAAnil K Sood - Departments of Psychology, Urology, Obstetrics & Gynecology, Holden Comprehensive Cancer Center, University of Iowa, E11 Seashore Hall, Iowa City, IA 52242, USASusan K Lutgendorf - Departments of Psychology, Urology, Obstetrics & Gynecology, Holden Comprehensive Cancer Center, University of Iowa, E11 Seashore Hall, Iowa City, IA 52242, USA
- Resource Type
- Journal article
- Publication Details
- Immunology and allergy clinics of North America, Vol.31(1), pp.109-132
- DOI
- 10.1016/j.iac.2010.09.001
- PMID
- 21094927
- PMCID
- PMC3011980
- NLM abbreviation
- Immunol Allergy Clin North Am
- ISSN
- 0889-8561
- eISSN
- 1557-8607
- Publisher
- Elsevier Inc
- Grant note
- R21 CA133343 / National Center for Research Resources KL2 RR0205012 / Clinical and Translational Science Award R01 CA110793, RO1 CA109298; P50 CA083693 / National Cancer Institute to SKL R01 CA140933; R01 CA104825 / National Cancer Institute to ESC
- Language
- English
- Date published
- 2011
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute; Obstetrics and Gynecology; Urology
- Record Identifier
- 9984065877402771
Metrics
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