Journal article
Biochemical Testing in Neuroendocrine Tumors
Endocrinology and metabolism clinics of North America, Vol.46(3), pp.669-677
09/2017
DOI: 10.1016/j.ecl.2017.04.004
PMCID: PMC5777173
PMID: 28760232
Abstract
Neuroendocrine cells are widely distributed throughout the body. They can produce, store, and secrete peptides and biogenic amines. Neuroendocrine tumors (NETs) are rare, but most are found in the intestine, pancreas, and lung. NETs may cause specific hormonal symptoms (eg, carcinoid syndrome) or appear nonfunctional. Blood or urine concentrations of tumor-secreted amines and peptides have been used as biomarkers in the diagnosis and management of NETs. This article focuses on currently available biochemical testing of blood or urine for gastroenteropancreatic and lung NETs and discusses the limitations of these tests and the potential role of newer multianalyte markers for NET management.
Details
- Title: Subtitle
- Biochemical Testing in Neuroendocrine Tumors
- Creators
- Vidya Aluri - University of IowaJoseph S Dillon - Division of Endocrinology, University of Iowa, 200 Hawkins Drive, Iowa City, Iowa 52242, USA. Electronic address: joseph-dillon@uiowa.edu.
- Resource Type
- Journal article
- Publication Details
- Endocrinology and metabolism clinics of North America, Vol.46(3), pp.669-677
- DOI
- 10.1016/j.ecl.2017.04.004
- PMID
- 28760232
- PMCID
- PMC5777173
- NLM abbreviation
- Endocrinol Metab Clin North Am
- ISSN
- 0889-8529
- eISSN
- 1558-4410
- Grant note
- P50 CA174521 / NCI NIH HHS
- Language
- English
- Date published
- 09/2017
- Academic Unit
- Fraternal Order of Eagles Diabetes Research Center; Endocrinology and Metabolism; Internal Medicine
- Record Identifier
- 9984361855302771
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