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Biofilm Formation by Salmonella enterica Serovar Typhimurium and Escherichia coli on Epithelial Cells following Mixed Inoculations
Journal article   Open access   Peer reviewed

Biofilm Formation by Salmonella enterica Serovar Typhimurium and Escherichia coli on Epithelial Cells following Mixed Inoculations

Cristina L. C Esteves, Bradley D Jones and Steven Clegg
Infection and immunity, Vol.73(8), pp.5198-5203
08/2005
DOI: 10.1128/IAI.73.8.5198-5203.2005
PMCID: PMC1201217
PMID: 16041039
url
https://doi.org/10.1128/IAI.73.8.5198-5203.2005View
Published (Version of record) Open Access

Abstract

Biofilms were formed by inoculations of Salmonella enterica serovar Typhimurium and Escherichia coli on HEp-2 cells. Inoculations of S. enterica serovar Typhimurium and E. coli resulted in the formation of an extensive biofilm of S. enterica serovar Typhimurium. In experiments where an E. coli biofilm was first formed followed by challenge with S. enterica serovar Typhimurium, there was significant biofilm formation by S. enterica serovar Typhimurium. The results of this study indicate that S. enterica serovar Typhimurium can outgrow E. coli in heterologous infections and displace E. coli when it forms a biofilm on HEp-2 cells.
Bacterial Infections

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