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Biomarkers in psychiatry: methodological issues
Journal article   Peer reviewed

Biomarkers in psychiatry: methodological issues

Helena Chmura Kraemer, Susan K Schultz and Stephan Arndt
The American journal of geriatric psychiatry, Vol.10(6), pp.653-659
11/2002
DOI: 10.1097/00019442-200211000-00004
PMID: 12427574

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Abstract

Particularly in psychiatry, biological measures are increasingly sought to detect exposure to toxic agents, to assist in early identification of illness, and to enhance diagnostic certainty, provide prognostic information, and permit the mapping of outcome in a variety of disorders. The authors explore the fundamental criteria necessary to designate a biological measure as a "biomarker" and discuss the potential applications, limitations, and hazards of such markers. Authors discuss methods for establishing the validity of a biomarker. Finally, they convey a word of caution about overinterpreting the clinical or scientific value of any biological measure.
Biomarkers - analysis Humans Mental Disorders - psychology

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