Journal article
Blood flow to respiratory, cardiac, and limb muscles in dogs during graded exercise
The American journal of physiology, Vol.231(5 Pt. 1), pp.1515-1519
11/1976
DOI: 10.1152/ajplegacy.1976.231.5.1515
PMID: 998797
Abstract
The distribution of cardiac output was analyzed in six dogs, with the animals at rest and running on a level treadmill for 3 min at 3-4 mph (mild exercise) and 3 min at 6-8 mph (moderate exercise). Organ flows were measured using 25-mug-diam radioactive microspheres. Cardiac output averaged 2.5, 4.6, and 5.7 liters/min, for rest, mild exercise, and moderate exercise, respectively. The greatest change was in diaphragmatic flow which increased by 275% with mild exercise and 500% with moderate exercise. Flow to intercostal muscles increased by 160 and 186%, to the exercising gastrocnemius muscle by 153 and 224%, and to cardiac muscle by 57 and 109% during mild and moderate exercise, respectively. Renal and cerebral flows did not change significantly. Significant decreases in flow occurred in the small and large intestines during moderate exercise. It is concluded that the increase in cardiac output during submaximal exercise was redistributed in a manner which limited flow to the brain, intestines, and kidneys and increased flow flow to the diaphragm, heart, and limb muscles.
Details
- Title: Subtitle
- Blood flow to respiratory, cardiac, and limb muscles in dogs during graded exercise
- Creators
- David E FixlerJames M AtkinsJere H MitchellLawrence D Horwitz
- Resource Type
- Journal article
- Publication Details
- The American journal of physiology, Vol.231(5 Pt. 1), pp.1515-1519
- DOI
- 10.1152/ajplegacy.1976.231.5.1515
- PMID
- 998797
- ISSN
- 0002-9513
- eISSN
- 2163-5773
- Language
- English
- Date published
- 11/1976
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984656600602771
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