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Blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulation
Journal article   Peer reviewed

Blood oxygenation changes resulting from suprathreshold transcranial magnetic stimulation

Richard H. Thomson, Jerome J. Maller, Zafiris J. Daskalakis and Paul B. Fitzgerald
Brain stimulation, Vol.4(3), pp.165-168
07/01/2011
DOI: 10.1016/j.brs.2010.10.003
PMID: 21777877
url
https://doaj.org/article/2b2d6541ec3640d3b74ab1dbb403236fView
Open Access

Abstract

The hemodynamic response to low-intensity transcranial magnetic stimulation (TMS) has previously been demonstrated at motor cortex using near infrared spectroscopy (NIRS). To investigate the effect of TMS on oxy-hemoglobin (HbO) at prefrontal cortex, both subthreshold and suprathreshold TMS relative to resting motor threshold (rMT) were applied at typical intensities used in experimental settings. Although there was no significant change after 90% and 110% rMT TMS, there was a significant drop in MO after 130% rMT TMS. This drop was maximal at approximately 8 seconds post-TMS. This study may have implications for determining appropriate TMS intensities when stimulating nonmotor areas. (C) 2011 Elsevier Inc. All rights reserved.
Clinical Neurology Life Sciences & Biomedicine Neurosciences Neurosciences & Neurology Science & Technology

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