Blood warms as it flows retrograde from a femoral cannulation site to the carotid artery during cardiopulmonary bypass

F Dexter; B J Hindman; J Cutkomp; T Smith

doi:10.1177/026765919400900604

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Blood warms as it flows retrograde from a femoral cannulation site to the carotid artery during cardiopulmonary bypass

Journal article

Peer reviewed

Blood warms as it flows retrograde from a femoral cannulation site to the carotid artery during cardiopulmonary bypass

F Dexter, B J Hindman, J Cutkomp and T Smith

Perfusion, Vol.9(6), pp.393-397

1994

DOI: 10.1177/026765919400900604

PMID: 7696741

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Abstract

Hypothermia protects the brain from injury during cardiopulmonary bypass and hypothermic circulatory arrest. However, when the arterial cannula is at sites other than the ascending aorta, brain cooling before circulatory arrest may be incomplete, contributing to poor neurological outcome. The authors performed an experiment using a rabbit model of cardiopulmonary bypass with femoral arterial perfusion. Arterial perfusate and carotid artery temperatures were simultaneously measured in six rabbits undergoing cardiopulmonary bypass, three with femoral artery cannulation, and three with subclavian artery cannulation. The subclavian artery site was chosen as a surrogate for ascending aortic cannulation. Carotid blood temperature was 3.7 degrees C to 0.3 degree C warmer than arterial perfusate temperature during femoral arterial perfusion. The temperature difference decreased over time (p = 0.0007). The temperature gradient was significantly less (p = 0.002) when subclavian arterial perfusion was used. Carotid blood temperature was 1.1 degrees C to 0.0 degree C warmer than arterial perfusate temperature during subclavian cannulation. The authors conclude that when femoral perfusion cooling is used, blood is warmed as it flows in a retrograde direction in the descending aorta to the carotid artery.

Rabbits

Animals

Catheterization

Carotid Arteries - physiopathology

Perfusion

Blood Physiological Phenomena

Subclavian Artery - physiopathology

Femoral Artery

Cardiopulmonary Bypass

Body Temperature

Regional Blood Flow

Details

Title: Subtitle: Blood warms as it flows retrograde from a femoral cannulation site to the carotid artery during cardiopulmonary bypass
Creators: F Dexter - Department of Anesthesia, University of Iowa, Iowa City 52242
B J Hindman
J Cutkomp
T Smith
Resource Type: Journal article
Publication Details: Perfusion, Vol.9(6), pp.393-397
Publisher: England
DOI: 10.1177/026765919400900604
PMID: 7696741
ISSN: 0267-6591
eISSN: 1477-111X
Grant note: 1R 01HL47159 / NHLBI NIH HHS
Language: English
Date published: 1994
Academic Unit: Health Management and Policy; Anesthesia
Record Identifier: 9983806379702771

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