Logo image
Back
Bone Density and Fractures in HIV-infected Postmenopausal Women: A Systematic Review
Journal article   Peer reviewed

Bone Density and Fractures in HIV-infected Postmenopausal Women: A Systematic Review

Yamnia I. Cortés, Michael T. Yin and Nancy K. Reame
The Journal of the Association of Nurses in AIDS Care, Vol.26(4), pp.387-398
07/01/2015
DOI: 10.1016/j.jana.2015.03.005
PMCID: PMC4573531
PMID: 26066693

View Online

Abstract

With the development of effective antiretroviral therapy, HIV-infected women are living longer and transitioning through menopause. The purpose of our study was to systematically examine the evidence that menopause is an additional risk predictor for osteoporosis and fractures in HIV-infected women. Electronic databases were searched for studies of low bone density or fractures in HIV-infected postmenopausal women. Studies that met the inclusion criteria (n = 10) were appraised using a validated quality assessment tool. The majority of studies were rated as good quality and the remaining were fair. The prevalence of osteoporosis reported in these studies ranged from 7.3% to 84% and 0.7% to 23% in HIV-infected and uninfected postmenopausal women, respectively. In the two qualifying studies, postmenopausal status was not a predictor of fractures in HIV-infected women. Findings suggest that HIV care providers should accurately assess postmenopausal status and modifiable risk factors for osteoporosis in all older HIV-infected women.
 bone mineral density (BMD) fractures HIV menopause

Details

Metrics

11 Record Views
21 Times Cited - Web of Science
Logo image