Journal article
Bone health in children with recurrent and chronic pancreatitis: A multi-center cross sectional analysis
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], Vol.23(7), pp.755-760
11/2023
DOI: 10.1016/j.pan.2023.08.006
PMCID: PMC10843133
PMID: 37723006
Abstract
Bone health of children with acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) is not well studied.
This retrospective study was performed at three sites and included data from INSPPIRE-2.
Of the 87 children in the study: 46 had ARP (53%), 41 had CP (47%). Mean age was 13.6 ± 3.9 years at last DXA scan. The prevalence of low height-for-age (Z-score < −2) (13%, 10/78) and low bone mineral density (BMD) adjusted for height (Z-score < −2) (6.4%, 5/78) were higher than a healthy reference sample (2.5%, p < 0.0001 and p = 0.03, respectively).
Children with ARP or CP have lower height and BMD than healthy peers. Attention to deficits in growth and bone mineral accrual in children with pancreatic disease is warranted.
Details
- Title: Subtitle
- Bone health in children with recurrent and chronic pancreatitis: A multi-center cross sectional analysis
- Creators
- Maisam Abu-El-Haija - Cincinnati Children's Hospital Medical CenterLindsey Hornung - Cincinnati Children's Hospital Medical CenterKate Ellery - University of Pittsburgh Medical CenterDouglas S. Fishman - Baylor College of MedicineTanja Y. Gonska - Hospital for Sick ChildrenCheryl Gariepy - Nationwide Children's HospitalMark Lowe - Washington University in St. LouisKatie Larson Ode - University of IowaAsim Maqbool - Children's Hospital of PhiladelphiaMaria Mascarenhas - Children's Hospital of PhiladelphiaVeronique D. Morinville - Montreal Children's HospitalChee Y. Ooi - Sydney Children's HospitalEmily R. Perito - University of California, San FranciscoSarah Jane Schwarzenberg - University of Minnesota Children's HospitalZachary M. Sellers - Stanford UniversityBabette S. Zemel - Children's Hospital of PhiladelphiaYing Yuan - The University of Texas MD Anderson Cancer CenterFuchenchu Wang - The University of Texas MD Anderson Cancer CenterAliye Uc - University of IowaHeidi J. Kalkwarf - University of Cincinnati Medical CenterConsortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC)
- Resource Type
- Journal article
- Publication Details
- Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], Vol.23(7), pp.755-760
- DOI
- 10.1016/j.pan.2023.08.006
- PMID
- 37723006
- PMCID
- PMC10843133
- NLM abbreviation
- Pancreatology
- ISSN
- 1424-3903
- eISSN
- 1424-3911
- Publisher
- Elsevier B.V
- Grant note
- DOI: 10.13039/100000002, name: National Institutes of Health; DOI: 10.13039/100000062, name: National Institute of Diabetes and Digestive and Kidney Diseases, award: U01DK108328, U01 DK108334, K23DK118190
- Language
- English
- Electronic publication date
- 08/2023
- Date published
- 11/2023
- Academic Unit
- Endocrinology and Diabetes; Stead Family Department of Pediatrics; Radiation Oncology; Gastroenterology, Hepatology, Pancreatology, and Nutrition
- Record Identifier
- 9984463128202771
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