Brachytherapy Future Directions

J Adam Martin Cunha; Ryan Flynn; Cédric Bélanger; Cameron Callaghan; Yusung Kim; Xun Jia; Zhe Chen; Luc Beaulieu

doi:10.1016/j.semradonc.2019.09.001

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Journal article

Peer reviewed

Brachytherapy Future Directions

J Adam Martin Cunha, Ryan Flynn, Cédric Bélanger, Cameron Callaghan, Yusung Kim, Xun Jia, Zhe Chen and Luc Beaulieu

Seminars in radiation oncology, Vol.30(1), pp.94-106

01/2020

DOI: 10.1016/j.semradonc.2019.09.001

PMID: 31727305

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Abstract

Brachytherapy has advanced dramatically in the last decade due largely to improvements in applicators, imaging, treatment planning, and use of clinical trials. In addition, current research in brachytherapy technology continues to change how we deliver this treatment modality. The future of brachytherapy lies in the ability of new technologies to overcome real or perceived barriers. The focus for this manuscript is on specific tools that have or are near to being introduced in the clinic. First, we explore the impact electromagnetic tracking technologies can have on brachytherapy implants and planning workflow. This is followed by an overview of the use of 3D printing and its ability to help tailor brachytherapy implants. Next, we discuss advances in self-shielded applicators and intensity-modulated brachytherapy technology. The manuscript closes out with 2 sections on treatment planning. First is a discussion of biological optimization and its potential as compared with current techniques (eg, based on physical dosimetry). And lastly, a section on optimization treatment planning efficiencies in which we explore the potential for machine learning in brachytherapy. As recent clinical evidence continues to show excellent outcomes, this is an exciting time to practice brachytherapy. With the new technologies presented here, the future is even brighter.

Brachytherapy - methods

Brachytherapy - trends

Electromagnetic Phenomena

Female

Humans

Male

Neoplasms - radiotherapy

Printing, Three-Dimensional

Prostheses and Implants

Radiotherapy Dosage

Radiotherapy Planning, Computer-Assisted - methods

Radiotherapy, Image-Guided

Workflow

Details

Title: Subtitle: Brachytherapy Future Directions
Creators: J Adam Martin Cunha - University of California System
Ryan Flynn - University of Iowa
Cédric Bélanger - Université Laval
Cameron Callaghan - University of Iowa
Yusung Kim - University of Iowa
Xun Jia - The University of Texas Southwestern Medical Center
Zhe Chen - Yale University
Luc Beaulieu - Université Laval
Resource Type: Journal article
Publication Details: Seminars in radiation oncology, Vol.30(1), pp.94-106
DOI: 10.1016/j.semradonc.2019.09.001
PMID: 31727305
ISSN: 1053-4296
eISSN: 1532-9461
Language: English
Date published: 01/2020
Academic Unit: Radiation Oncology
Record Identifier: 9984313083902771

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