Breast Milk for Term and Preterm Infants-Own Mother's Milk or Donor Milk?

Reka A. Vass; Gabriella Kiss; Edward F. Bell; Robert D. Roghair; Attila Miseta; Jozsef Bodis; Simone Funke; Tibor Ertl

doi:10.3390/nu13020424

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Breast Milk for Term and Preterm Infants-Own Mother's Milk or Donor Milk?

Journal article

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Breast Milk for Term and Preterm Infants-Own Mother's Milk or Donor Milk?

Reka A. Vass, Gabriella Kiss, Edward F. Bell, Robert D. Roghair, Attila Miseta, Jozsef Bodis, Simone Funke and Tibor Ertl

Nutrients, Vol.13(2), pp.1-10

02/01/2021

DOI: 10.3390/nu13020424

PMCID: PMC7912320

PMID: 33525560

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Abstract

Hormones are important biological regulators, controlling development and physiological processes throughout life. We investigated pituitary hormones such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL) and total protein levels during the first 6 months of lactation. Breast milk samples were collected every fourth week of lactation from mothers who gave birth to preterm (n = 14) or term (n = 16) infants. Donor milk is suggested when own mother's milk is not available; therefore, we collected breast milk samples before and after Holder pasteurization (HoP) from the Breast Milk Collection Center of Pecs, Hungary. Three infant formulas prepared in the Neonatal Intensive Care Unit of the University of Pecs were tested at three different time points. Our aim was to examine the hormone content of own mother's milk and donor milk. There were no significant changes over time in the concentrations of any hormone. Preterm milk had higher PRL (28.2 +/- 2.5 vs. 19.3 +/- 2.3 ng/mL) and LH (36.3 +/- 8.8 vs. 15.9 +/- 4.1 mIU/L) concentrations than term milk during the first 6 months of lactation. Total protein and FSH concentrations did not differ between preterm and term breast milk. Holder pasteurization decreased the PRL concentration (30.4 +/- 1.8 vs. 14.4 +/- 0.6 ng/mL) and did not affect gonadotropin levels of donor milk. Infant formulas have higher total protein content than breast milk but do not contain detectable levels of pituitary hormones. Differences were detected in the content of pituitary hormones produced for preterm and term infants. Divergence between feeding options offers opportunities for improvement of nutritional guidelines for both hospital and home feeding practices.

Life Sciences & Biomedicine

Nutrition & Dietetics

Science & Technology

Details

Title: Subtitle: Breast Milk for Term and Preterm Infants-Own Mother's Milk or Donor Milk?
Creators: Reka A. Vass - University of Pecs
Gabriella Kiss - University of Pecs
Edward F. Bell - University of Iowa
Robert D. Roghair - University of Iowa
Attila Miseta - University of Pecs
Jozsef Bodis - University of Pecs
Simone Funke - University of Pecs
Tibor Ertl - University of Pecs
Resource Type: Journal article
Publication Details: Nutrients, Vol.13(2), pp.1-10
DOI: 10.3390/nu13020424
PMID: 33525560
PMCID: PMC7912320
NLM abbreviation: Nutrients
ISSN: 2072-6643
eISSN: 2072-6643
Publisher: Mdpi
Number of pages: 10
Grant note: Medical School of the University of Pecs UNKP-20-4-I / New National Excellence Program of the Ministry for Innovation and Technology from the source of the National Research, Development and Innovation Fund GINOP-2.3.2-15-2016-00021 / National Laboratory on Human Reproduction
Language: English
Date published: 02/01/2021
Academic Unit: Stead Family Department of Pediatrics; Neonatology
Record Identifier: 9984354035402771

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